Related Experiment Video
Updated: May 24, 2026

Methods to Quantify Pharmacologically Induced Alterations in Motor Function in Human Incomplete SCI
Published on: April 18, 2011
[New knowledge of spasticity and its treatment]
Jakob Lorentzen1, Maria Willerslev-Olsen, Clarissa Crone
1Center for Rett syndrom, Kennedy Centret, Gammel Landevej 7, 2600 Glostrup, Denmark. jlorentzen@ifi.ku.dk
None:
Spasticity is a frequently used diagnosis, and anti-spastic medication is used widespread. In this systematic review article we highlight difficulties in diagnosing spasticity correctly and thus limit the value of the diagnosis in ensuring the best possible treatment. We review recent neuroscience research and conclude that it is necessary to develop better tools for clinical diagnosis of spasticity in order to avoid potential malpractice and to limit treatment with anti-spastic drugs for patients with documented increased reflex-mediated muscle tone as their main annoyance.
Related Concept Videos
Spinal Cord Injury ll: Pathophysiology
Alterations in Muscle Tone ll
Myasthenia Gravis: Overview and Treatment
These antibodies interfere with the function of the nicotinic receptors in three ways: by binding to the receptor and disrupting acetylcholine binding; by causing cross-linking of receptors which leads...
Secondary Spinal Cord Injury llI: Pathophysiology
