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Prospects for a statistical theory of LC/TOFMS data

Andreas Ipsen1, Timothy M D Ebbels

  • 1Biomolecular Medicine, Department of Surgery and Cancer, Faculty of Medicine, Sir Alexander Fleming Building, Imperial College London, London, SW7 2AZ, UK. andreas.ipsen06@imperial.ac.uk

Journal of the American Society for Mass Spectrometry
|March 1, 2012
PubMed
Summary

This study introduces a rigorous statistical method for analyzing liquid chromatography-time-of-flight mass spectrometry (LC/TOFMS) data. It provides a validated probability distribution enabling formal statistical tests for more reliable inferences from inexact measurements.

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