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Body composition after bone marrow transplantation in childhood
Kathy Ruble1, Matthew Hayat, Kerry J Stewart
1School of Medicine, Johns Hopkins University, Baltimore, MD, USA. rubleka@jhmi.edu
Oncology Nursing Forum
|March 1, 2012
Summary
Childhood bone marrow transplant (BMT) survivors often have elevated body fat and central obesity, which standard BMI criteria miss. Nurses should assess for these conditions and provide resources for healthy weight management.
Area of Science:
- Pediatric Oncology
- Transplantation Medicine
- Body Composition Analysis
Background:
- Childhood bone marrow transplantation (BMT) survivors face long-term health risks.
- Body composition changes and fat distribution are critical aspects of survivorship care.
Purpose of the Study:
- To characterize body composition and fat distribution in childhood BMT survivors.
- To evaluate the efficacy of CDC criteria in identifying survivors with excess body fat.
Main Methods:
- Cross-sectional descriptive study of 48 childhood BMT survivors.
- Utilized dual-energy x-ray absorptiometry (DXA) for body composition analysis.
- Assessed total body fat percentage and central obesity.
Main Results:
- 54% of survivors exceeded healthy body fat recommendations; 31% had central obesity.
- Total body irradiation was linked to higher body fat and central obesity.
- Body Mass Index (BMI) criteria failed to accurately identify elevated body fat in survivors.
Conclusions:
- Childhood BMT survivors are at significant risk for obesity and central obesity.
- Standard BMI screening is insufficient for detecting these body composition abnormalities.
- Nursing assessment and targeted patient education are crucial for managing BMT survivor health.
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