[Amyloidosis of fundus oculi tissues in senile maculopathy (a clinico-morphological study)]

The authors analyze the findings of clinical and morphologic studies of the pathologic changes in fundus oculi tissues of 3 patients who died with senile macular dystrophy, examined in life time by ophthalmoscopic technique with transformed light. The sclera, vascular coating, retina, macula retinae, optic nerve region were thoroughly studied with the use of review histological, histochemical methods, selective test for amyloid, thiazine red fluorescent histochemical method, and thioflavin T fluorescence. In 2 of the 3 cases amyloid degeneration in the presence of amyloid deposits in choroid vessels, arterial plexus vessels round the optic nerve presence of amyloid deposits in choroid vessels, arterial plexus vessels round the optic nerve orifice, in Bruch's membrane and in the sclera. Retinal vessels, optic nerve and its coatings were intact. Further investigations are to follow.