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Current status of antidotal therapies in acute human intoxications
P Lheureux1, D Even-Adin, R Askenasi
1Emergency Department, Erasme University Hospital, ULB, Brussels.
Abstract:
The purpose of this work is a review of usefulness, indications and handling of some antidotes which are at our disposal for therapeutic use since several years, especially naloxone, flumazenil, Fab fragments of digoxin specific antibodies, hydroxocobalamine, 4-methyl-pyrazole, N-acetylcystein or the new metal chelators. Older clinically relevant substances are also reviewed.