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Related Concept Videos

Atomic Nuclei: Magnetic Resonance01:05

Atomic Nuclei: Magnetic Resonance

The number of nuclear spins aligned in the lower energy state is slightly greater than those in the higher energy state. In the presence of an external magnetic field, as the spins precess at the Larmor frequency, the excess population results in a net magnetization oriented along the z axis. When a pulse or a short burst of radio waves at the Larmor frequency is applied along the x axis, the coupling of frequencies causes resonance and flips the nuclear spins of the excess population from the...
NMR Spectroscopy: Spin–Spin Coupling01:08

NMR Spectroscopy: Spin–Spin Coupling

The spin state of an NMR-active nucleus can have a slight effect on its immediate electronic environment. This effect propagates through the intervening bonds and affects the electronic environments of NMR-active nuclei up to three bonds away; occasionally, even farther. This phenomenon is called spin–spin coupling or J-coupling. Coupling interactions are mutual and result in small changes in the absorption frequencies of both nuclei involved. While nuclei of the same element are involved in...
Atomic Nuclei: Nuclear Spin State Overview01:03

Atomic Nuclei: Nuclear Spin State Overview

NMR-active nuclei have energy levels called 'spin states' that are associated with the orientations of their nuclear magnetic moments. In the absence of a magnetic field, the nuclear magnetic moments are randomly oriented, and the spin states are degenerate. When an external magnetic field is applied, the spin states have only 2 + 1 orientations available to them. A proton with = ½ has two available orientations. Similarly, for a quadrupolar nucleus with a nuclear spin value of one, the...
NMR Spectrometers: Resolution and Error Correction01:14

NMR Spectrometers: Resolution and Error Correction

When magnetic nuclei in a sample achieve resonance and undergo relaxation, the signal detected in NMR is an approximately exponential free induction decay. Fourier transform of an exponential decay yields a Lorentzian peak in the frequency domain. Lorentzian peaks in an NMR spectrum are defined by their amplitude, full width at half maximum, and position, where the peak width is governed by the spin-spin relaxation time alone. In real experiments, however, the applied magnetic field is rendered...
¹H NMR: Interpreting Distorted and Overlapping Signals01:02

¹H NMR: Interpreting Distorted and Overlapping Signals

Spin systems where the difference in chemical shifts of the coupled nuclei is greater than ten times J are called first-order spin systems. These nuclei are weakly coupled, and their chemical shifts and coupling constant can generally be estimated from the well-separated signals in the spectrum.
As Δν decreases and the signals move closer, the doublets appear increasingly distorted. The intensities of the inner lines increase at the cost of those of the outer lines as the signals are slanted or...
Atomic Nuclei: Nuclear Relaxation Processes01:23

Atomic Nuclei: Nuclear Relaxation Processes

In the absence of an external magnetic field, nuclear spin states are degenerate and randomly oriented. When a magnetic field is applied, the spins begin to precess and orient themselves along (lower energy) or against (higher energy) the direction of the field. At equilibrium, a slight excess population of spins exists in the lower energy state. Because the direction of the magnetic field is fixed as the z-axis,  the precessing magnetic moments are randomly oriented around the z-axis. This...

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High-Temperature and High-Pressure In situ Magic Angle Spinning Nuclear Magnetic Resonance Spectroscopy
08:55

High-Temperature and High-Pressure In situ Magic Angle Spinning Nuclear Magnetic Resonance Spectroscopy

Published on: October 9, 2020

Paramagnetic solid-state magic-angle spinning NMR spectroscopy.

Guido Pintacuda1, Gwendal Kervern

  • 1Centre de RMN à Très Hauts Champs, Institut de Sciences Analytiques, Université de Lyon, UMR 5280 CNRS/Ecole Normale Supérieure de Lyon/Université Claude Bernard Lyon 1, 69100, Villeurbanne, France, guido.pintacuda@ens-lyon.fr.

Topics in Current Chemistry
|March 7, 2012
PubMed
Summary
This summary is machine-generated.

Recent advances in solid-state Nuclear Magnetic Resonance (NMR) enable analysis of new molecules. This technique provides detailed molecular structure and electronic configuration insights for catalysts and biomolecules.

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High-Temperature and High-Pressure In situ Magic Angle Spinning Nuclear Magnetic Resonance Spectroscopy
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Area of Science:

  • Chemistry
  • Biochemistry
  • Materials Science

Background:

  • Solid-state Nuclear Magnetic Resonance (NMR) has undergone significant technical advancements.
  • These improvements expand its applicability to novel substrate analyses.

Purpose of the Study:

  • To highlight the broad implications of new solid-state NMR capabilities.
  • To emphasize the utility of paramagnetic compounds in structural analysis via solid-state NMR.

Main Methods:

  • Utilizing solid-state NMR spectroscopy.
  • Analyzing signals from paramagnetic compounds.

Main Results:

  • Solid-state NMR now allows analysis of new substrate classes.
  • Paramagnetic centers provide well-defined structural information.
  • Direct experimental access to molecular electronic configuration is achieved.

Conclusions:

  • Solid-state NMR offers detailed insights into molecular geometry.
  • The technique is applicable to both small catalysts and large biomolecules.
  • These advancements significantly benefit the research community.