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Updated: May 24, 2026
Retinal Vascular Reactivity as Assessed by Optical Coherence Tomography Angiography
Published on: March 26, 2020
Comparison of optic nerve head parameters using Heidelberg Retina Tomograph 3 and spectral-domain optical coherence
Shino Sato1, Kazuyuki Hirooka, Tetsuya Baba
1Department of Ophthalmology, Kagawa University Faculty of Medicine, 1750-1 Ikenobe, Miki, Kagawa, Japan.
Background:
To assess the agreement between the Heidelberg Retina Tomograph and Cirrus spectral-domain optical coherence tomography (Cirrus HD-OCT [Carl Zeiss Meditec, Dublin, CA, USA]) when measuring optic disc parameters.
Design:
Prospective, cross-sectional study.
Participants:
A total of 96 glaucoma patients and 21 normal subjects were analysed.
Methods:
Optic nerve head measurements, including disc area, rim area, cup-to-disc ratio and cup volume were obtained using both the Cirrus HD-OCT and Heidelberg Retina Tomograph 3 (Heidelberg Engineering GmbH, Heidelberg, Germany).
Main Outcome Measurements:
Bland-Altman plots were used to evaluate the agreement between each of the optic disc parameters.
Results:
Although Cirrus HD-OCT values were smaller than Heidelberg Retina Tomograph 3 values for the disc and rim areas, overall the Cirrus HD-OCT and Heidelberg Retina Tomograph 3 measurements were highly correlated (r = 0.657 to 0.821). As compared with Heidelberg Retina Tomograph 3, disc and rim areas tended to be minimized by Cirrus HD-OCT, especially when there were large disc and rim areas, although there was no relationship between the discrepancy and the level of measurement of the cup-to-disc ratio. The optical coherence tomography overestimated the Heidelberg Retina Tomograph-determined cup volume, especially when there were large cup volumes.
Conclusions:
Bland-Altman analyses revealed that with the exception of the cup-to-disc ratio, there was poor agreement between the Cirrus HD-OCT and Heidelberg Retina Tomograph 3 morphometric measurements. In addition, with the exception of the cup-to-disc ratio, the optic nerve head measurements could not be directly compared between the Cirrus HD-OCT and Heidelberg Retina Tomograph 3.
