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Pattern recognition receptors in immune disorders affecting the skin.

Heleen D de Koning1, Anna Simon, Patrick L J M Zeeuwen

  • 1Department of Dermatology, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands. h.dekoning@derma.umcn.nl

Journal of Innate Immunity
|March 9, 2012
PubMed
Summary

Pattern recognition receptors (PRRs) protect against pathogens, but their overactivity can harm the host. Dysfunctional PRRs are linked to skin immune disorders, prompting new immunomodulatory therapies.

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