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Related Concept Videos

Major Somatic Sensory Pathways01:28

Major Somatic Sensory Pathways

Sensory impulses related to touch, pressure, vibration, and proprioception from various body parts, such as the limbs, trunk, neck, and posterior head, travel to the cerebral cortex through the posterior column-medial lemniscus pathway. The pathway’s name derives from the two white-matter tracts that convey the impulses: the spinal cord's posterior column and the brainstem's medial lemniscus. First-order sensory neurons extend their axons into the spinal cord, forming the posterior columns...
Neural Circuits01:25

Neural Circuits

Neural circuits and neuronal pools are two of the main structures found in the nervous system. Neural circuits are networks of neurons that work together to carry out a specific task or process. They consist of interconnected neurons and glial cells, which provide structural and metabolic support.
Neuronal pools are collections of nerve cells with similar functions and interact through chemical and electrical signals. These pools include both interneurons (the central neural circuit nodes that...
What is a Sensory System?01:31

What is a Sensory System?

Sensory systems detect stimuli—such as light and sound waves—and transduce them into neural signals that can be interpreted by the nervous system. In addition to external stimuli detected by the senses, some sensory systems detect internal stimuli—such as the proprioceptors in muscles and tendons that send feedback about limb position.
Diencephalon: Thalamus and Information Relay01:27

Diencephalon: Thalamus and Information Relay

The thalamus, often called “the gateway to the cerebral cortex,” is vital in processing and directing sensory and motor signals throughout the brain. Almost all inputs destined for the cerebral cortex, except for olfactory signals, are relayed through the thalamus. The thalamus is  a sophisticated relay station, channeling information from various brain regions to the cerebral cortex, as well as a filter, prioritizing certain signals over others based on current physiological states or needs.
Overview of Somatic Sensory Pathways01:29

Overview of Somatic Sensory Pathways

Somatic sensory or somatosensory pathways refer to the neural pathways that carry information related to touch, pressure, pain, temperature, and proprioception from the skin, muscles, tendons, and joints to the brain. These pathways involve several stages of processing and integration of sensory information.
The somatosensory system is divided into three main pathways: the dorsal (or posterior) column-medial lemniscus, spinothalamic (or anterolateral), and spinocerebellar pathways.
The dorsal...
Neural Regulation01:37

Neural Regulation

Digestion begins with a cephalic phase that prepares the digestive system to receive food. When our brain processes visual or olfactory information about food, it triggers impulses in the cranial nerves innervating the salivary glands and stomach to prepare for food.

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Related Experiment Video

Updated: May 24, 2026

Modeling the Functional Network for Spatial Navigation in the Human Brain
05:55

Modeling the Functional Network for Spatial Navigation in the Human Brain

Published on: October 13, 2023

[Neural mechanisms for navigation].

Masato Taira1

  • 1Department of Cognitive Neurobiology, Tokyo Medical and Dental University, Tokyo, Japan.

Brain and Nerve = Shinkei Kenkyu No Shinpo
|March 10, 2012
PubMed
Summary

Researchers found route-selective navigation neurons in the medial parietal region (MPR). Inactivating these neurons caused monkeys to get lost, suggesting MPR is critical for spatial navigation and integrating movement and location data.

Area of Science:

  • Neuroscience
  • Cognitive Science
  • Spatial Cognition

Context:

  • Understanding the neural mechanisms underlying spatial navigation is crucial for fields like robotics and neuroscience.
  • Previous research has identified various brain regions involved in navigation, but the specific role of the medial parietal region (MPR) remains less understood.

Purpose:

  • To investigate the role of the medial parietal region (MPR) in spatial navigation.
  • To identify neurons in the MPR that are involved in processing navigational information.
  • To determine the causal contribution of MPR activity to successful navigation.

Summary:

  • Neural activity was recorded in the monkey MPR during active navigation in a virtual environment.
  • Navigation neurons were identified whose activity was modulated in a route-selective manner, responding differently to the same location and movement depending on the ongoing route.

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Assessing Human Spatial Navigation in a Virtual Space and its Sensitivity to Exercise
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Assessing Human Spatial Navigation in a Virtual Space and its Sensitivity to Exercise

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Using Pharmacological Manipulation and High-precision Radio Telemetry to Study the Spatial Cognition in Free-ranging Animals
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Using Pharmacological Manipulation and High-precision Radio Telemetry to Study the Spatial Cognition in Free-ranging Animals

Published on: November 6, 2016

Related Experiment Videos

Last Updated: May 24, 2026

Modeling the Functional Network for Spatial Navigation in the Human Brain
05:55

Modeling the Functional Network for Spatial Navigation in the Human Brain

Published on: October 13, 2023

Assessing Human Spatial Navigation in a Virtual Space and its Sensitivity to Exercise
06:17

Assessing Human Spatial Navigation in a Virtual Space and its Sensitivity to Exercise

Published on: January 26, 2024

Using Pharmacological Manipulation and High-precision Radio Telemetry to Study the Spatial Cognition in Free-ranging Animals
08:28

Using Pharmacological Manipulation and High-precision Radio Telemetry to Study the Spatial Cognition in Free-ranging Animals

Published on: November 6, 2016

  • Reversible inactivation of MPR neurons using muscimol led to disorientation and the inability to complete the navigation task.

    • Impact:

    • These findings highlight the critical role of the medial parietal region (MPR) in integrating location and self-movement information for effective navigation.
    • The study provides a neural basis for understanding how the brain constructs and maintains a sense of direction and place.
    • This research has implications for understanding navigation deficits in neurological disorders and for developing advanced navigation systems.