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Strategies to screen for stage B as a heart failure prevention intervention
1Cardiovascular Division, Mayo Clinic, 200 First Street Southwest, Rochester, MN 55905, USA. redfield.margaret@mayo.edu
Insights
Preventing heart failure (HF) is crucial, especially in aging populations. Research is advancing to identify targets and strategies, including focusing on Stage B heart failure, for effective HF prevention.
Area of Science:
- Cardiology
- Public Health
- Preventive Medicine
Background:
- Heart failure (HF) prevention is a significant public health goal.
- An aging global population faces increasing cardiovascular and noncardiovascular risks.
- Current understanding of HF pathophysiology is evolving, necessitating new prevention strategies.
Purpose of the Study:
- To explore novel approaches for heart failure prevention.
- To highlight the need for integrated strategies combining therapeutic targets with health care delivery and behavioral modification.
- To investigate the potential of targeting Stage B heart failure.
Main Methods:
- Review of current understanding of cardiac and noncardiac abnormalities predisposing to HF.
- Analysis of the requirements for successful prevention strategies.
- Exploration of health care delivery and behavioral modification sciences.
Main Results:
- Advancing understanding of HF pathophysiology.
- Identification of the need for multifaceted prevention approaches.
- Potential of targeting Stage B heart failure as a key strategy.
Conclusions:
- Effective heart failure prevention requires identifying therapeutic targets.
- Integrating health care delivery and behavioral modification is essential.
- Targeting Stage B heart failure offers a promising avenue for prevention.
Abstract:
Heart failure (HF) prevention is an indisputably laudable goal, albeit with undefined global public health impact in an increasingly elderly population with competing cardiovascular and noncardiovascular risks for morbidity and mortality. The understanding of cardiac and noncardiac structural and functional abnormalities that predispose to the diverse clinical HF syndrome is rapidly advancing, and novel approaches for prevention and treatment are needed. Successful approaches mandate not only identification of discrete therapeutic targets but also research into the developing sciences of health care delivery and behavioral modification. Targeting Stage B HF represents one such potential strategy.
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