Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Microbial Biosensors01:17

Microbial Biosensors

Microbial biosensors are analytical devices that utilize living microbes to detect specific substances through measurable signals. These devices consist of two main components: biosensing organisms and signal-transducing elements. Biosensing organisms, such as Escherichia coli or Saccharomyces cerevisiae, are typically housed in multiwell plates connected to transducers, enabling rapid, real-time detection of target analytes.Signal Generation MechanismWhen a target analyte—such as...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Fully Collective Superradiant Lasing with Vanishing Sensitivity to Cavity Length Vibrations.

Physical review letters·2026
Same author

ICM 2025: New Technologies like Artificial Intelligence, Robotics, and Anti-Biofilm.

The Journal of arthroplasty·2025
Same author

Discrete Subdomains Establish Epigenetic Diversity in Subtelomeric Heterochromatin.

bioRxiv : the preprint server for biology·2025
Same author

Parametric modeling of deformable linear objects for robotic outfitting and maintenance of space systems.

Frontiers in robotics and AI·2025
Same author

Metabolic-Associated Steatotic Liver Disease: From Molecular Mechanisms to Novel Therapies.

International journal of hepatology·2025
Same author

George J. Reul, MD: A Tribute.

Texas Heart Institute journal·2025
Same journal

Four-in-one multifunctional CoCu-NC@AuPt nanozyme integrated M13 phage-displayed nanobody based multimodal lateral flow immunoassay for bovine lactoferrin detection.

Biosensors & bioelectronics·2026
Same journal

A novel capillary-driven dual-mode imaging flow cytometry system for malaria parasite detection and quantification.

Biosensors & bioelectronics·2026
Same journal

Liver-targeted alkaline phosphatase-activatable fluorescent probe for imaging liver fibrosis and screening anti-fibrotic natural products.

Biosensors & bioelectronics·2026
Same journal

GLASS-seq: a gel-anchored, ligation-assisted, scalable biosensing platform for low-cost regional spatial transcriptomics.

Biosensors & bioelectronics·2026
Same journal

CRISPR/Cas12a-based dual-modal signal platform using MIL-101(Fe) for colorimetric and electron spin resonance detection of HPV-16 nucleic acid.

Biosensors & bioelectronics·2026
Same journal

Fully automated centrifugal microfluidic system for self-calibrating isothermal nucleic acid quantification.

Biosensors & bioelectronics·2026
See all related articles

Related Experiment Video

Updated: May 24, 2026

Printed Glycan Array: A Sensitive Technique for the Analysis of the Repertoire of Circulating Anti-carbohydrate Antibodies in Small Animals
08:49

Printed Glycan Array: A Sensitive Technique for the Analysis of the Repertoire of Circulating Anti-carbohydrate Antibodies in Small Animals

Published on: February 14, 2019

Microelectrode array biosensor for studying carbohydrate-mediated interactions.

Jeffrey W Chamberlain1, Karl Maurer, John Cooper

  • 1Department of Bioengineering, University of Washington, Seattle, WA 98195, USA. jeffwc@uw.edu

Biosensors & Bioelectronics
|March 13, 2012
PubMed
Summary
This summary is machine-generated.

This study introduces a novel microelectrode array platform for studying carbohydrate interactions in infections. The system effectively screens antiadhesives, showing promise for developing new infection prevention strategies.

More Related Videos

Multi-analyte Biochip (MAB) Based on All-solid-state Ion-selective Electrodes (ASSISE) for Physiological Research
08:03

Multi-analyte Biochip (MAB) Based on All-solid-state Ion-selective Electrodes (ASSISE) for Physiological Research

Published on: April 18, 2013

Chemically-blocked Antibody Microarray for Multiplexed High-throughput Profiling of Specific Protein Glycosylation in Complex Samples
13:21

Chemically-blocked Antibody Microarray for Multiplexed High-throughput Profiling of Specific Protein Glycosylation in Complex Samples

Published on: May 4, 2012

Related Experiment Videos

Last Updated: May 24, 2026

Printed Glycan Array: A Sensitive Technique for the Analysis of the Repertoire of Circulating Anti-carbohydrate Antibodies in Small Animals
08:49

Printed Glycan Array: A Sensitive Technique for the Analysis of the Repertoire of Circulating Anti-carbohydrate Antibodies in Small Animals

Published on: February 14, 2019

Multi-analyte Biochip (MAB) Based on All-solid-state Ion-selective Electrodes (ASSISE) for Physiological Research
08:03

Multi-analyte Biochip (MAB) Based on All-solid-state Ion-selective Electrodes (ASSISE) for Physiological Research

Published on: April 18, 2013

Chemically-blocked Antibody Microarray for Multiplexed High-throughput Profiling of Specific Protein Glycosylation in Complex Samples
13:21

Chemically-blocked Antibody Microarray for Multiplexed High-throughput Profiling of Specific Protein Glycosylation in Complex Samples

Published on: May 4, 2012

Area of Science:

  • Biotechnology
  • Biomaterials Science
  • Infectious Disease Research

Background:

  • Carbohydrate interactions are crucial in host-pathogen dynamics, presenting therapeutic targets.
  • Developing effective antiadhesives requires robust screening methods for carbohydrate-mediated binding.

Purpose of the Study:

  • To develop a versatile microelectrode array platform for investigating carbohydrate-mediated protein and bacterial binding.
  • To establish a generalizable method for screening inhibitors of host-microbe interactions.

Main Methods:

  • Functionalization of microelectrodes with carbohydrates via pyrrole polymerization and neoglycoconjugate physisorption.
  • Detection of carbohydrate-binding proteins (lectins) using fluorescent and electrochemical methods.
  • Assessment of whole-cell binding using Escherichia coli and Salmonella enterica strains.

Main Results:

  • Successful immobilization and bioactivity confirmation of carbohydrates on microelectrodes.
  • Demonstrated platform capability for analyzing whole-cell binding interactions.
  • Validated dose-dependent inhibition of Salmonella enterica binding by a soluble antiadhesive.

Conclusions:

  • The developed microelectrode array platform is effective for studying carbohydrate-mediated host-pathogen interactions.
  • This platform offers a generalizable approach for screening carbohydrate-based antiadhesives.
  • The findings support the development of novel strategies for preventing bacterial and viral infections.