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Updated: May 23, 2026
07:47
Multiomics Analysis of TMEM200A as a Pan-Cancer Biomarker
Published on: September 15, 2023
Metabolomics in cancer: a bench-to-bedside intersection.
Wederson M Claudino1, Priscila H Goncalves, Angelo di Leo
1Department of Internal Medicine, Wayne State University School of Medicine, Detroit, MI 48201, USA.
Critical Reviews in Oncology/Hematology
|March 21, 2012
Summary
Metabolomics offers new insights into cancer biology, aiding in understanding tumor processes and developing targeted therapies. This approach helps refine cancer staging and identify biomarkers for treatment response and toxicity.
Area of Science:
- Oncology
- Metabolomics
- Cancer Biology
Background:
- Oncology is rapidly advancing due to research yielding deeper understanding of tumor biology and novel therapies.
- Metabolomics is an emerging 'omics' field poised to significantly enhance cancer biology knowledge.
Purpose of the Study:
- To explore the role of metabolomics in understanding cancer processes.
- To investigate metabolomics for improving cancer staging and tumor characterization.
- To assess metabolomics in identifying predictive biomarkers for treatment response and toxicity.
Main Methods:
- Literature review of metabolomic studies in oncology.
- Analysis of current applications of metabolomics in cancer research.
- Synthesis of findings on metabolomics for biomarker discovery.
Main Results:
- Metabolomics provides a functional readout of cellular processes relevant to cancer.
- Metabolomic profiles can differentiate tumor types and stages.
- Potential for metabolomics-derived biomarkers predicting therapeutic outcomes.
Conclusions:
- Metabolomics is a valuable tool for advancing cancer research and clinical practice.
- Further research is needed to translate metabolomic findings into routine clinical use.
- Metabolomics holds promise for personalized cancer medicine through biomarker development.
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