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A randomized controlled trial of belimumab for the treatment of active systemic lupus erythematosus

Ryan G Gamble1, Robert P Dellavalle

  • 1School of Medicine, University of Colorado Anschutz Medical Campus, Aurora, CO, USA.

Archives of Dermatology
|March 21, 2012
PubMed
Abstract

No abstract available in PubMed .

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Blinding

Blinding is a commonly used method of not telling participants which treatment a subject is receiving. Blinding is a critical part of a randomized control trial or RCT. It reduces the bias that affects the results. In an RCT, blinding is used in the form of a placebo. A placebo effect occurs when untreated subjects falsely believe they have received the treatment and report improved symptoms. A placebo or a dummy treatment is administered to subjects to negate the bias caused by such an effect.