[Clinical aspects and histopathology of the Cogan-Reese syndrome]

The present paper reports on a 55 year-old patient who had been suffering from progressive essential iris atrophy in her left eye since the age of 24. Ten years later she developed partial secondary angel-closure glaucoma that failed to respond to repeated surgical treatment. Twenty years after onset of the disease, pigmented nodules appeared on the left iris, leading to the diagnosis of Cogan-Reese syndrome. Finally, 30 years after onset of the disease, the blind and painful eye was enucleated. The typical histologic findings in Cogan-Reese syndrome were confirmed by light and electron microscopy.