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Published on: January 9, 2019
Cochlear implantation in mitochondrial deafness due to A7445G mutation
1Department of Otolaryngology, Christchurch Public Hospital, Christchurch, New Zealand. rsalter@clear.net.nz
Objective:
This study aimed to determine if cochlear implantation (CI) improved speech discrimination in the New Zealand pedigree with the A7445G mitochondrial DNA (mtDNA) mutation and sensorineural hearing loss (SNHL).
Methods:
Nine patients had their speech discrimination and pure tone audiograms evaluated. Pre- and post-implant results were compared. Type of CI and patient age at implantation was recorded.
Results:
Speech discrimination testing shows greatly improved functional hearing after CI in this group of patients.
Discussion:
Individuals with mtDNA-related SNHL should be identified by screening and offered assessment for CI suitability because functional hearing improves after CI.
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