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Updated: May 23, 2026

Assessment of Child Anthropometry in a Large Epidemiologic Study
Published on: February 2, 2017
Obesity is not associated with increased mortality and morbidity in critically ill children
Vi Lier Goh1, Martin K Wakeham, Ruta Brazauskas
1Division of Pediatric Gastroenterology, Hepatology, and Nutrition, Medical College of Wisconsin, Milwaukee, Wisconsin 53226, USA.
Insights
Critically ill children who are overweight or obese and require mechanical ventilation do not have increased mortality or longer hospital stays. Obesity does not appear to negatively impact outcomes for these pediatric patients.
Area of Science:
- Pediatric critical care medicine
- Pediatric intensive care
- Obesity research
Background:
- Childhood obesity is a growing concern with potential health implications.
- The impact of obesity on outcomes for critically ill children requiring mechanical ventilation is not well-established.
Purpose of the Study:
- To investigate the association between obesity and outcomes in critically ill children requiring invasive mechanical ventilation.
- To compare mortality, duration of mechanical ventilation, and length of stay (LOS) in pediatric intensive care units (PICUs) among children with varying weight categories.
Main Methods:
- Retrospective cohort study of 1030 children (2-18 years) admitted to a PICU requiring invasive ventilation between 2005-2009.
- Patients categorized by weight z-score: normal, overweight, obese, and severely obese. Underweight patients excluded.
- Outcomes analyzed: mortality, ventilator days, and PICU LOS using univariate and multivariate regression analyses.
Main Results:
- No significant difference in risk-adjusted mortality rates between normal-weight, overweight, obese, and severely obese children.
- Total mechanical ventilation days and PICU length of stay were similar across all weight categories after adjusting for risk factors.
Conclusions:
- Overweight, obese, and severely obese children requiring invasive mechanical ventilation in the PICU experience similar mortality and resource utilization compared to normal-weight children.
- Obesity status does not appear to be an independent risk factor for adverse outcomes in this critically ill pediatric population.
Aim:
To evaluate the effect of obesity on mortality, length of mechanical ventilation, and length of stay (LOS) in critically ill children.
Methods:
Retrospective cohort study in 2- to 18-year-olds, admitted to the pediatric intensive care unit (PICU) at the Children's Hospital of Wisconsin from 2005-2009 who required invasive ventilation. Weight z score was used to categorize patients as normal (-1.89 to 1.04), overweight (1.05-1.65), obese (1.66-2.33), and severely obese (>2.33). Underweight patients were excluded. Age, gender, admission type, Pediatric Index of Mortality 2 score, operative status, trauma status, admission Pediatric Outcome Performance Category, and diagnosis categories were also collected. The outcomes were mortality, total ventilator days, and PICU LOS. Univariate analysis was used to compare the groups, and multivariate logistic regression was used to compare mortality. Total ventilation days and LOS were modeled with linear regression.
Results:
In total, 1030 patients were included in the study, with 753 normal weight, 137 overweight, 76 obese, and 64 severely obese. The risk-adjusted mortality rates in overweight (odds ratio [OR], 1.06; 95% confidence interval [CI], 0.62-1.82), obese (OR, 0.68; 95% CI, 0.31-1.48), and severely obese patients (OR, 1.02; 95% CI, 0.45-2.34) were not significantly different compared with the normal-weight group. Total ventilation days (P = .9628) and PICU LOS (P = .8431) were not significantly different between the groups after adjusting for risk factors.
Conclusion:
Critically ill overweight, obese, and severely obese children who require invasive mechanical ventilation have similar mortality, length of stay in the PICU, and ventilator days as compared with normal-weight children.
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