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Updated: May 23, 2026

High-resolution Tandem Mass Spectrometry for Studying Chemical Constituents of Gynura bicolor DC
Published on: February 2, 2024
Hypoglycemic constituents of Gynura divaricata subsp. formosana
Shen-Chieh Chou1, Lee-Ming Chuang, Shoei-Sheng Lee
1Research Center for Biodiversity and Graduate Institute of Ecology and Evolutionary Biology, China Medical University, Taichung 40402, Taiwan.
Abstract:
Gynura divaricata Kitam. subsp. formosana is a folk medicine used as a hypoglycemic agent for diabetes patients in Taiwan. Guided by the hexose transport assay, the hypoglycemic constituents of the aerial part of this plant were disclosed through chromatographic methods. They are fructooligosaccharides, including beta-D-fructofuranose, sucrose, 1-kestose, nystose, and 1(F)-beta-fructofuranosylnystose. The hexose transport assay indicated that nystose was the most potent among these compounds, showing a 46.7% difference from pinitol in the stimulation index at a concentration of 0.5 mg/mL.
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