Related Experiment Video
Updated: Aug 7, 2026

19:53
Single-stage Dynamic Reanimation of the Smile in Irreversible Facial Paralysis by Free Functional Muscle Transfer
Published on: March 1, 2015
Bilateral hypoglossal nerve paralysis after irradiation therapy
The Annals of Otology, Rhinology, and Laryngology
|July 1, 1979
Summary
Head and neck irradiation therapy can cause delayed cranial nerve paralysis due to tissue fibrosis. This case highlights bilateral hypoglossal nerve paresis occurring three years post-therapy.
Area of Science:
- Neurology
- Oncology
- Radiotherapy
Background:
- Head and neck cancers are frequently treated with irradiation therapy.
- Irradiation can cause long-term side effects, including nerve damage.
Observation:
- Delayed neurological deficits can occur years after radiotherapy.
- Fibrosis and infiltration of nerves are common mechanisms for post-irradiation complications.
Findings:
- The hypoglossal nerve is particularly susceptible to delayed effects of irradiation.
- A case of bilateral hypoglossal paresis is presented, manifesting three years after therapy.
Implications:
- Awareness of delayed cranial nerve palsies is crucial for clinicians managing head and neck cancer survivors.
- Long-term follow-up is essential to detect and manage radiation-induced neurological complications.

