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Related Concept Videos

Allergic Reactions02:06

Allergic Reactions

Overview
Antiasthma Drugs: Mast Cell Stabilizers and Anti-IgE Drugs01:25

Antiasthma Drugs: Mast Cell Stabilizers and Anti-IgE Drugs

Asthma is a chronic respiratory condition for which new therapeutic avenues, including anti-inflammatory drugs like mast cell stabilizers and anti-IgE treatments, continue to be developed.
Mast cell stabilizers, such as cromolyn (also known as sodium cromoglycate) and nedocromil (Tilade), are effective drugs in asthma management. These stabilizers hinder histamine release by skillfully obstructing the activation of mast cells and other cellular entities. Notably, they navigate this task without...
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Allergic Reactions: Anaphylaxis

Anaphylaxis is a severe, life-threatening hypersensitivity reaction mediated by Immunoglobulin E (IgE) antibodies. When IgE binds to allergens, it triggers the release of mediators– histamine, leukotrienes, and prostaglandins from mast cells and basophils. These mediators cause vasodilation, edema, and inflammation, leading to various symptoms.The primary allergens causing anaphylaxis include food items (e.g., peanuts, shellfish), drugs (e.g., penicillin, asparaginase, corticotropin, heparin),...
Hypersensitivities01:30

Hypersensitivities

Hypersensitivity, also known as a hypersensitivity reaction or allergic reaction, is a condition where the body's immune system reacts abnormally to a foreign substance. Such substances, that cause hypersensitivity are referred to as an allergen, could be something typically harmless to most people, like pollen or certain foods.
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Allergic Drug Reactions01:27

Allergic Drug Reactions

Allergic reactions related to drugs are hypersensitivity responses driven by the immune system and bear no connection to the drug's therapeutic action. While drugs in isolation do not trigger an immune response, they can interact with endogenous proteins to form antigens. These antigens stimulate lymphocytes to produce antibodies. IgE-type antibodies attach themselves to mast cells. Upon subsequent exposure to the same stimulus, the antigen-antibody interaction is initiated, unleashing numerous...
Asthma I: Introduction01:28

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Asthma is a chronic inflammatory disorder of the airways characterized by variable airflow obstruction and heightened bronchial responsiveness to a wide range of triggers. The underlying inflammation leads to airway swelling, mucus hypersecretion, and smooth muscle constriction, all of which narrow the airway lumen and impede airflow. Clinically, asthma presents with recurrent episodes of wheezing, shortness of breath, chest tightness, and coughing, symptoms that typically vary in intensity and...

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Related Experiment Video

Updated: May 23, 2026

A Component-resolved Diagnostic Approach for a Study on Grass Pollen Allergens in Chinese Southerners with Allergic Rhinitis and/or Asthma
06:34

A Component-resolved Diagnostic Approach for a Study on Grass Pollen Allergens in Chinese Southerners with Allergic Rhinitis and/or Asthma

Published on: June 4, 2017

[Pollen allergy and immunotherapy].

P Schmid-Grendelmeier1

  • 1Allergiestation, Dermatologische Klinik, Universitätsspital Zürich. peter.schmid@usz.ch

Therapeutische Umschau. Revue Therapeutique
|April 6, 2012
PubMed
Summary
This summary is machine-generated.

Pollinosis, or hay fever, affects many in Switzerland. Allergen-specific immunotherapy (SIT) offers significant benefits for over 80% of patients, with new methods enhancing its effectiveness and safety.

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Last Updated: May 23, 2026

A Component-resolved Diagnostic Approach for a Study on Grass Pollen Allergens in Chinese Southerners with Allergic Rhinitis and/or Asthma
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Area of Science:

  • Allergy and Immunology
  • Clinical Medicine

Context:

  • Pollinosis affects up to 25% of the Swiss population, with a substantial increase over the last century.
  • Key allergens include birch, ash, and grass pollens, as well as mugwort.

Purpose:

  • To review the diagnosis and treatment of pollinosis, focusing on allergen-specific immunotherapy (SIT).
  • To highlight factors influencing SIT success and emerging advancements.

Summary:

  • Diagnosis involves medical history, skin tests, and specific IgE serum determination.
  • Treatment options include allergen avoidance, pharmacotherapy, and SIT.
  • Subcutaneous immunotherapy (SCIT) is the primary choice, while sublingual immunotherapy (SLIT) is a complementary approach, particularly effective for grass pollen allergies.
  • Component-resolved diagnosis aids in more specific patient and allergen selection.
  • SIT benefits over 80% of pollinosis patients when properly managed.

Impact:

  • Successful SIT requires careful patient and allergen selection, appropriate application regimens, and good patient adherence.
  • Emerging research focuses on modified application regimens and molecular technologies to further improve SIT efficacy, safety, and acceptance.
  • Component-resolved diagnostics represent a valuable tool for personalized allergy treatment strategies.