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Related Concept Videos

Allergic Reactions02:06

Allergic Reactions

Overview
Asthma I: Introduction01:28

Asthma I: Introduction

Asthma is a chronic inflammatory disorder of the airways characterized by variable airflow obstruction and heightened bronchial responsiveness to a wide range of triggers. The underlying inflammation leads to airway swelling, mucus hypersecretion, and smooth muscle constriction, all of which narrow the airway lumen and impede airflow. Clinically, asthma presents with recurrent episodes of wheezing, shortness of breath, chest tightness, and coughing, symptoms that typically vary in intensity and...
Allergic Reactions: Anaphylaxis01:30

Allergic Reactions: Anaphylaxis

Anaphylaxis is a severe, life-threatening hypersensitivity reaction mediated by Immunoglobulin E (IgE) antibodies. When IgE binds to allergens, it triggers the release of mediators– histamine, leukotrienes, and prostaglandins from mast cells and basophils. These mediators cause vasodilation, edema, and inflammation, leading to various symptoms.The primary allergens causing anaphylaxis include food items (e.g., peanuts, shellfish), drugs (e.g., penicillin, asparaginase, corticotropin, heparin),...
Asthma-I: Introduction01:29

Asthma-I: Introduction

Asthma is a chronic respiratory ailment that requires careful management due to its varying symptoms and influencing factors. It is characterized by airway inflammation, bronchial hyperresponsiveness, and reversible airflow obstruction, leading to symptoms like wheezing, shortness of breath, chest tightness, and coughing. The symptom frequency and intensity may vary considerably over time. It is also linked to immune system responses to allergens and irritants, highlighting the complex...
Asthma: Pathogenesis and Management01:20

Asthma: Pathogenesis and Management

Asthma is a chronic pulmonary condition involving inflammation of the airways, hyper-reactivity, and reversible obstruction of the airways. This condition can significantly impact a person's quality of life, making breathing difficult and leading to distressing symptoms.
Asthma is classified as allergic and non-allergic. Allergens such as dust mites, pollen, and pet dander trigger allergic asthma, while factors like cold air, intense emotions, or exercise can induce non-allergic asthma.
Asthma-II: Pathophysiology and Classification01:26

Asthma-II: Pathophysiology and Classification

Asthma is a prevalent chronic respiratory condition marked by inflammation and hyperresponsiveness of the airways. Its pathophysiology involves complex interactions among inflammatory pathways, immune responses, and neural mechanisms.
Additionally, environmental and genetic factors play crucial roles in determining an individual's susceptibility to asthma and the severity of their condition.
Critical processes in asthma pathophysiology include:

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Related Experiment Video

Updated: May 23, 2026

Identification and Characterization of Immunogenic RNA Species in HDM Allergens that Modulate Eosinophilic Lung Inflammation
08:44

Identification and Characterization of Immunogenic RNA Species in HDM Allergens that Modulate Eosinophilic Lung Inflammation

Published on: May 30, 2020

[House dust mite allergy].

A Carrard1, C Pichler

  • 1Universitätsklinik für Rheumatologie, Inselspital Bern und Klinische Immunologie und Allergologie, Inselspital Bern.

Therapeutische Umschau. Revue Therapeutique
|April 6, 2012
PubMed
Summary
This summary is machine-generated.

House dust mites, found globally, cause chronic allergies through inhaled enzymes. Avoidance measures and immunotherapy offer effective relief for allergic rhinitis and asthma.

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Symptom Assessment of Patients with Allergic Rhinitis Using an Allergen Exposure Chamber
08:47

Symptom Assessment of Patients with Allergic Rhinitis Using an Allergen Exposure Chamber

Published on: March 3, 2023

Related Experiment Videos

Last Updated: May 23, 2026

Identification and Characterization of Immunogenic RNA Species in HDM Allergens that Modulate Eosinophilic Lung Inflammation
08:44

Identification and Characterization of Immunogenic RNA Species in HDM Allergens that Modulate Eosinophilic Lung Inflammation

Published on: May 30, 2020

Symptom Assessment of Patients with Allergic Rhinitis Using an Allergen Exposure Chamber
08:47

Symptom Assessment of Patients with Allergic Rhinitis Using an Allergen Exposure Chamber

Published on: March 3, 2023

Area of Science:

  • Allergy and Immunology
  • Environmental Health
  • Dermatology

Background:

  • House dust mites are ubiquitous allergens found worldwide, thriving in humid conditions.
  • Enzymes from mite gastrointestinal tracts are potent allergens inducing chronic respiratory diseases like asthma.
  • Mite allergens accumulate in domestic environments, particularly in mattresses and carpets, feeding on human dander.

Purpose of the Study:

  • To summarize the global prevalence and impact of house dust mite allergies.
  • To discuss diagnostic challenges and therapeutic strategies for house dust mite-induced diseases.
  • To highlight the efficacy of avoidance measures and immunotherapy.

Main Methods:

  • Literature review of house dust mite allergenicity and clinical manifestations.
  • Analysis of diagnostic approaches, including skin testing.
  • Evaluation of therapeutic interventions such as topical steroids, avoidance strategies, and immunotherapy.

Main Results:

  • Inhalation of mite allergens leads to chronic allergic rhinitis and persistent asthma.
  • Delayed diagnosis is common due to slowly aggravating symptoms.
  • House dust mite avoidance measures, like ventilation and encasings, show good clinical results.
  • Specific immunotherapy with mite extracts is effective in both children and adults.

Conclusions:

  • House dust mite allergy is a significant global health issue requiring effective management.
  • Integrated therapeutic approaches combining avoidance, medication, and immunotherapy are crucial.
  • Advancements in recombinant allergens promise improved diagnostics and therapeutics.