Related Experiment Video

Updated: Jan 20, 2026

Quaternary Structure Modeling Through Chemical Cross-Linking Mass Spectrometry: Extending TX-MS Jupyter Reports
05:18

Quaternary Structure Modeling Through Chemical Cross-Linking Mass Spectrometry: Extending TX-MS Jupyter Reports

Published on: October 20, 2021

2.6K

Chemical cross-linking in biology

M Das, C F Fox

    Annual Review of Biophysics and Bioengineering
    |January 1, 1979
    PubMed
    Summary

    No abstract available in PubMed .

    More Related Videos

    Combining Chemical Cross-linking and Mass Spectrometry of Intact Protein Complexes to Study the Architecture of Multi-subunit Protein Assemblies10:01

    Combining Chemical Cross-linking and Mass Spectrometry of Intact Protein Complexes to Study the Architecture of Multi-subunit Protein Assemblies

    Published on: November 28, 2017

    20.3K
    A Facile and Efficient Approach for the Production of Reversible Disulfide Cross-linked Micelles09:57

    A Facile and Efficient Approach for the Production of Reversible Disulfide Cross-linked Micelles

    Published on: December 23, 2016

    9.3K

    Related Concept Videos

    Quaternary Structure Modeling Through Chemical Cross-Linking Mass Spectrometry: Extending TX-MS Jupyter Reports05:18

    Quaternary Structure Modeling Through Chemical Cross-Linking Mass Spectrometry: Extending TX-MS Jupyter Reports

    Targeted cross-linking mass spectrometry creates quaternary protein structure models using mass spectrometry data acquired using up to three different acquisition protocols. When executed as a simplified workflow on the Cheetah-MS web server, the results are reported in a Jupyter Notebook. Here, we demonstrate the technical aspects of how the Jupyter Notebook can be extended for a more in-depth...
    2.6K
    Combining Chemical Cross-linking and Mass Spectrometry of Intact Protein Complexes to Study the Architecture of Multi-subunit Protein Assemblies10:01

    Combining Chemical Cross-linking and Mass Spectrometry of Intact Protein Complexes to Study the Architecture of Multi-subunit Protein Assemblies

    The architecture of protein complexes is essential for their function. Combining various mass spectrometric techniques proved powerful to study their assembly. We provide protocols for chemical cross-linking and native mass spectrometry and show how these complementary techniques help to elucidate the architecture of multi-subunit protein...
    20.3K
    A Facile and Efficient Approach for the Production of Reversible Disulfide Cross-linked Micelles09:57

    A Facile and Efficient Approach for the Production of Reversible Disulfide Cross-linked Micelles

    To deliver cancer drugs to tumor sites with high specificity and reduced side effects, new methods based on nanoparticles are required. Here, we describe disulfide cross-linked micelles that can be easily prepared by hydrogen peroxide-mediated oxidation and are able to dissociate efficiently under a reducing tumor environment to release...
    9.3K
    The Preparation and Properties of Thermo-reversibly Cross-linked Rubber Via Diels-Alder Chemistry07:02

    The Preparation and Properties of Thermo-reversibly Cross-linked Rubber Via Diels-Alder Chemistry

    A simple two-step approach involving rubber modification and cross-linking yields fully reworkable, elastic rubber products.
    14.2K
    Free Radicals in Chemical Biology: from Chemical Behavior to Biomarker Development14:22

    Free Radicals in Chemical Biology: from Chemical Behavior to Biomarker Development

    Radical-based biomimetic chemistry has been applied to building-up libraries necessary for biomarker...
    20.7K
    Photo-Induced Cross-Linking of Unmodified Proteins (PICUP) Applied to Amyloidogenic Peptides08:40

    Photo-Induced Cross-Linking of Unmodified Proteins (PICUP) Applied to Amyloidogenic Peptides

    Photo-induced cross-linking of unmodified proteins (PICUP) allows characterization of oligomer size distribution in metastable protein mixtures. We demonstrate application of PICUP to three representative amyloidogenic peptides the 40- and 42-residue forms of amyloid β-protein, and calcitonin, and a control peptide growth-hormone releasing...
    21.9K