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A Computerized Test Battery to Study Pharmacodynamic Effects on the Central Nervous System of Cholinergic Drugs in Early Phase Drug Development
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COMT as a drug target for cognitive functions and dysfunctions

Diego Scheggia1, Sara Sannino, Maria Luisa Scattoni

  • 1Department of Neuroscience and Brain Technologies, Istituto Italiano di Tecnologia, Genova, Italy.

CNS & Neurological Disorders Drug Targets
|April 10, 2012
PubMed
Summary

Catechol-O-methyltransferase (COMT) impacts prefrontal cortex functions like memory and attention. Genetic variations in COMT influence cognitive abilities and predict responses to psychiatric medications, aiding personalized healthcare.

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