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Updated: May 23, 2026

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Anterior High-Resolution Optical Coherence Tomography in the Diagnosis and Therapeutic Monitoring of Ocular Surface Squamous Neoplasia
Published on: August 9, 2024
Sclerochoroidal calcifications imaged using enhanced depth imaging optical coherence tomography
Jithin Yohannan1, Roomasa Channa, Cathy W Dibernardo
1Retinal Imaging Research and Reading Center, Wilmer Eye Institute, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
Ocular Immunology and Inflammation
|April 11, 2012
Summary
Sclerochoroidal calcifications can mimic choroidal masses. Enhanced depth imaging optical coherence tomography (EDI-OCT) reveals unique features of these calcifications, aiding diagnosis.
Area of Science:
- Ophthalmology
- Medical Imaging
Background:
- Bilateral retinal lesions in an 85-year-old patient were initially suspected to be metastases.
- Diagnostic evaluation included slit-lamp biomicroscopy, funduscopy, fluorescein angiography, B-scan ultrasonography (U/S), and enhanced depth imaging optical coherence tomography (EDI-OCT).
Observation:
- B-scan U/S showed bilateral echo-dense choroidal consolidations with acoustic shadowing.
- EDI-OCT visualized hyper-reflective lesions with posterior decreased reflectivity.
Findings:
- The observed features were consistent with sclerochoroidal calcifications.
- EDI-OCT provided unique imaging characteristics of these lesions.
Implications:
- Sclerochoroidal calcifications should be considered in the differential diagnosis of choroidal masses.
- EDI-OCT is a valuable tool for identifying the characteristic appearance of sclerochoroidal calcifications.

