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Published on: September 5, 2017

Frosted branch angiitis in a woman with Mycobacterium tuberculosis infection

Huiying Zhao, Juan Guan, Li Zhou

    Ocular Immunology and Inflammation
    |April 11, 2012
    PubMed
    Abstract

    Insights

    Tuberculous meningitis can cause frosted branch angiitis, a rare condition affecting retinal blood vessels. Prompt treatment with anti-tuberculosis medications and steroids led to resolution of the angiitis.

    Area of Science:

    • Ophthalmology
    • Infectious Diseases
    • Neurology

    Background:

    • Tuberculous meningitis is a serious infection affecting the brain's membranes.
    • Frosted branch angiitis is a rare condition characterized by inflammation and white sheathing of retinal vessels.

    Observation:

    • A 27-year-old woman with tuberculous meningitis presented with acute blurred vision.
    • Ophthalmic examination revealed characteristic frosted branch angiitis in both eyes, with prominent white sheathing of retinal venules and arterioles.

    Findings:

    • The case demonstrates a direct link between Mycobacterium tuberculosis infection and the development of frosted branch angiitis.
    • Treatment with systemic anti-tuberculosis medications alongside corticosteroid therapy resulted in the resolution of ocular symptoms and angiitis.

    Implications:

    • This case highlights Mycobacterium tuberculosis as a potential cause of frosted branch angiitis.
    • Effective management involves addressing the underlying tuberculosis infection and utilizing anti-inflammatory treatment with steroids.

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