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[Liquorice-induced hypertension and hypokalaemia]
Mette Lundgren Nielsen1, Manan Pareek, Inger Andersen
1Kardiologisk Afdeling Y, Bispebjerg Hospital, Bispebjerg Bakke 23, 2400 København NV, Denmark. mettelundgren@gmail.com
Abstract:
Consumption of large amounts of liquorice can cause hypertension and hypokalaemia. Liquorice contains glycyrrhetinic acid, which inhibits the enzyme 11 beta-hydroxysteroid dehydrogenase type 2, and ultimately leads to an apparent mineralocorticoid excess syndrome. This case report describes a 50 year-old woman presenting with hypertension and hypokalaemia-induced limb paresis due to chronic liquorice ingestion. The patient was treated with potassium supplementation and spironolactone. Her blood pressure and electrolyte status normalised within a month after cessation of liquorice intake.
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