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A novel HLA-A*31 allele, A*31:57, identified by sequence-based typing

A H Lim1, S N Song, J Y Lee

  • 1Blood Transfusion Research Institute, Korean Red Cross, Seoul, Korea.

Tissue Antigens
|April 12, 2012
PubMed

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Genome-wide association studies or GWAS are used to identify whether common SNPs are associated with certain diseases. Suppose specific SNPs are more frequently observed in individuals with a particular disease than those without the disease. In that case, those SNPs are said to be associated with the disease. Chi-square analysis is performed to check the probability of the allele likely to be associated with the disease.
GWAS does not require the identification of the target gene involved in...