Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Test Cross01:39

Test Cross

Alleles are different forms of the same gene. Humans and other diploid organisms inherit two alleles of every gene, one from each parent.
Test Cross01:39

Test Cross

Alleles are different forms of the same gene. Humans and other diploid organisms inherit two alleles of every gene, one from each parent.
Dihybrid Crosses01:18

Dihybrid Crosses

Overview
Genome-wide Association Studies-GWAS01:11

Genome-wide Association Studies-GWAS

Genome-wide association studies or GWAS are used to identify whether common SNPs are associated with certain diseases. Suppose specific SNPs are more frequently observed in individuals with a particular disease than those without the disease. In that case, those SNPs are said to be associated with the disease. Chi-square analysis is performed to check the probability of the allele likely to be associated with the disease.
GWAS does not require the identification of the target gene involved in...
Epistasis Analysis01:09

Epistasis Analysis

Although Mendel chose seven unrelated traits in peas to study gene segregation, most traits involve multiple gene interactions that create a spectrum of phenotypes. When the interaction of various genes or alleles at different locations influences a phenotype, this is called epistasis. Epistasis often involves one gene masking or interfering with the expression of another (antagonistic epistasis). Epistasis often occurs when different genes are part of the same biochemical pathway. The...
Karyotyping01:17

Karyotyping

Overview

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Bioinformatics roadmap for characterizing the gut microbiome to study its interactions and associations with the gut mucosal immune system.

Mucosal immunology·2026
Same author

Right-Sided Aortic Arch Presenting as Chronic Cough in a 50-Year-Old Patient With DiGeorge Syndrome: A Report of a Rare Case.

Cureus·2026
Same author

The Mpox contextual data specification package: a data curation toolkit to support collaborative pathogen genomic surveillance.

Microbial genomics·2026
Same author

VIRUS-MVP: a framework for comprehensive surveillance of viral mutations and their functional impacts.

NAR genomics and bioinformatics·2025
Same author

Concurrent stimulation of diflufenican biodegradation and changes in the active microbiome in gravel revealed by Total RNA.

Microbiology spectrum·2025
Same author

SARS-CoV-2 genomic contextual data harmonization: recommendations from a mixed methods analysis of COVID-19 case report forms across Canada.

Archives of public health = Archives belges de sante publique·2025
Same journal

Assessment of lower incisor position and symphysis dimensions among different skeletal patterns in the Chhattisgarh population.

Bioinformation·2026
Same journal

Low T3 syndrome and short-term outcomes in patients with acute decompensated heart failure: A retrospective observational study.

Bioinformation·2026
Same journal

Cardiovascular risk prevention awareness and practices in type 2 diabetes: Linking HbA1c and lipid levels.

Bioinformation·2026
Same journal

Assessment of periodontal condition using basic periodontal examination scores: A retrospective clinical study.

Bioinformation·2026
Same journal

Comparative evaluation of osseointegration among different surface modification techniques in dental implants.

Bioinformation·2026
Same journal

Micro-osteoperforations' impact on orthodontic tooth movement rate: Split mouth research.

Bioinformation·2026
See all related articles

Related Experiment Video

Updated: May 23, 2026

Combined Immunofluorescence and DNA FISH on 3D-preserved Interphase Nuclei to Study Changes in 3D Nuclear Organization
13:55

Combined Immunofluorescence and DNA FISH on 3D-preserved Interphase Nuclei to Study Changes in 3D Nuclear Organization

Published on: February 3, 2013

Gene Locater: Genetic linkage analysis software using three-point testcross.

Muhammad Zohaib Anwar, Anoosha Sehar, Inayat-Ur Rehman

    Bioinformation
    |April 12, 2012
    PubMed
    Summary
    This summary is machine-generated.

    GENE LOCATOR is a new Java program that calculates recombination frequency for gene mapping. It offers a flexible, user-friendly interface for genetic linkage analysis and visualization, improving accuracy in genomics research.

    Keywords:
    Coefficient of CoincidenceDouble crossoversInterferenceRecombination FrequencySingle crossovers

    More Related Videos

    Candidate Gene Testing in Clinical Cohort Studies with Multiplexed Genotyping and Mass Spectrometry
    05:53

    Candidate Gene Testing in Clinical Cohort Studies with Multiplexed Genotyping and Mass Spectrometry

    Published on: June 21, 2018

    Frequency and Distribution of Crossovers in Caenorhabditis elegans Meiosis by SNP Genotyping using Real-time PCR
    06:18

    Frequency and Distribution of Crossovers in Caenorhabditis elegans Meiosis by SNP Genotyping using Real-time PCR

    Published on: July 11, 2025

    Related Experiment Videos

    Last Updated: May 23, 2026

    Combined Immunofluorescence and DNA FISH on 3D-preserved Interphase Nuclei to Study Changes in 3D Nuclear Organization
    13:55

    Combined Immunofluorescence and DNA FISH on 3D-preserved Interphase Nuclei to Study Changes in 3D Nuclear Organization

    Published on: February 3, 2013

    Candidate Gene Testing in Clinical Cohort Studies with Multiplexed Genotyping and Mass Spectrometry
    05:53

    Candidate Gene Testing in Clinical Cohort Studies with Multiplexed Genotyping and Mass Spectrometry

    Published on: June 21, 2018

    Frequency and Distribution of Crossovers in Caenorhabditis elegans Meiosis by SNP Genotyping using Real-time PCR
    06:18

    Frequency and Distribution of Crossovers in Caenorhabditis elegans Meiosis by SNP Genotyping using Real-time PCR

    Published on: July 11, 2025

    Area of Science:

    • Genetics
    • Genomics
    • Bioinformatics

    Background:

    • Accurate gene localization on chromosomes is crucial for understanding gene function, linkage, and recombination.
    • Gene position knowledge is essential for genome annotation and disease genetics studies.
    • Existing software for recombination frequency calculation often lacks flexibility and range.

    Purpose of the Study:

    • To introduce GENE LOCATOR, a customizable Java software for calculating recombination frequency.
    • To provide a flexible and user-friendly tool for genetic linkage analysis and visualization.
    • To enhance the accuracy of interference and coefficient of coincidence calculations.

    Main Methods:

    • Development of a fully customizable program in JAVA named GENE LOCATOR.
    • Implementation of an easy-to-use interface for genetic linkage analysis.
    • Inclusion of graphical visualization for linkage groups.

    Main Results:

    • GENE LOCATOR allows high flexibility in calculating genetic linkage and displaying linkage groups.
    • The software accurately calculates interference and coefficient of coincidence.
    • Sample datasets demonstrate the program's elevated accuracy.

    Conclusions:

    • GENE LOCATOR offers a significant advancement in calculating recombination frequency and analyzing genetic linkage.
    • The software's flexibility and graphical output aid in gene mapping and genomic studies.
    • GENE LOCATOR provides an accurate and accessible tool for the research community.