A new flavonol from Oxytropis ochrocephala Bunge

Area of Science:

• Phytochemistry
• Natural Product Chemistry
• Organic Chemistry

Background:

• Oxytropis ochrocephala Bunge is a plant species with potential medicinal properties.
• Flavonoids are a diverse class of natural compounds known for their biological activities.
• Previous research on this plant species may not be exhaustive.

Purpose of the Study:

• To isolate and characterize chemical constituents from Oxytropis ochrocephala Bunge.
• To identify novel compounds and elucidate their structures.
• To contribute to the understanding of the phytochemical profile of the plant.

Main Methods:

• Phytochemical investigation involving extraction and isolation techniques.
• Spectroscopic analyses including High-Resolution Electrospray Ionization Mass Spectrometry (HRESIMS).
• Infrared (IR) spectroscopy and comprehensive 1-D and 2-D Nuclear Magnetic Resonance (NMR) analyses for structural determination.

Main Results:

• Isolation of a new acylated flavonoid, 3-O-rhamnocitrin-6-O-benzoyl-β-D-glucopyranoside (1).
• Identification of five known flavonoids: rhamnocitrin (2), pratensein (3), (3R)-7,3'-dihydroxy-2',4'-dimethoxyisoflavan (4), (3R)-7,2'-dihydroxy-3',4'-dimethoxyisoflavan (5), and isoliquiritigenin (6).
• Complete structural elucidation of all isolated compounds was achieved through detailed spectroscopic data interpretation.

Conclusions:

• The study successfully identified and characterized six flavonoids from Oxytropis ochrocephala Bunge, including one novel compound.
• The findings expand the knowledge of the phytochemical diversity of the Oxytropis genus.
• The characterized compounds serve as a basis for further investigation into their potential biological activities and applications.