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Related Experiment Video

Updated: May 23, 2026

Measuring and Modeling Contractile Drying in Human Stratum Corneum
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Measuring and Modeling Contractile Drying in Human Stratum Corneum

Published on: March 1, 2017

In vivo stratum corneum over-hydration and water diffusion coefficient measurements using opto-thermal radiometry and

P Xiao1, W Wong, A M Cottenden

  • 1Photophysics Research Centre, London South Bank University, London, UK. xiaop@lsbu.ac.uk

International Journal of Cosmetic Science
|April 21, 2012
PubMed
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New methods using opto-thermal transient emission radiometry (OTTER) and evaporimetry accurately measure skin over-hydration. Skin water diffusion non-linearly depends on surface hydration, correlating with evaporative flux.

Area of Science:

  • Dermatology
  • Biophysics
  • Materials Science

Background:

  • Skin over-hydration is a prevalent issue, particularly for individuals using incontinence products.
  • Understanding stratum corneum (SC) water dynamics is crucial for managing skin health in such conditions.

Purpose of the Study:

  • To develop and validate a novel methodology for assessing SC over-hydration.
  • To quantify SC water diffusion coefficients and their relationship with hydration levels.

Main Methods:

  • Utilized opto-thermal transient emission radiometry (OTTER) to measure SC surface hydration and hydration gradients.
  • Employed evaporimetry to determine water vapor flux density (WVFD) over time.
  • Combined OTTER and evaporimetry data to analyze SC water diffusion coefficients.

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Last Updated: May 23, 2026

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Main Results:

  • Demonstrated a non-linear relationship between the SC water diffusion coefficient and SC surface hydration.
  • Established strong correlations between evaporative drying flux and SC surface hydration measured by OTTER.
  • Validated the combined OTTER-evaporimetry approach for SC hydration assessment.

Conclusions:

  • The developed method provides a robust way to study skin over-hydration and water transport.
  • Findings offer insights into the biophysical mechanisms of skin hydration relevant to incontinence care.
  • The study highlights the interdependence of SC hydration, water diffusion, and evaporative loss.