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Updated: May 23, 2026

Structured Approach to Colonoscopy Technique Optimization: A Single-Center Experience with Novice Endoscopists
Published on: July 11, 2025
Unsedated colonoscopy: A neverending story
Vittorio Terruzzi1, Silvia Paggi, Arnaldo Amato
1Vittorio Terruzzi, Silvia Paggi, Arnaldo Amato, Franco Radaelli, Division of Gastroenterology, Valduce Hospital, I-22100 Como, Italy.
Unsedated colonoscopy, while common in Asia and Europe, can be high quality and well tolerated. Alternative techniques like warm water irrigation or CO2 insufflation improve patient comfort and examination effectiveness.
Area of Science:
- Gastroenterology
- Medical Practice Variation
Background:
- Sedation and analgesia are standard for colonoscopy in Western countries.
- Unsedated colonoscopy is common in Europe and the Far East due to cultural differences.
- Patient and endoscopist attitudes influence sedation practices.
Purpose of the Study:
- To explore the feasibility and acceptance of unsedated colonoscopy.
- To highlight variations in colonoscopy sedation practices globally.
- To review alternative techniques for improving unsedated colonoscopy.
Main Methods:
- Literature review of studies on colonoscopy sedation practices.
- Analysis of data comparing sedated and unsedated colonoscopy.
- Examination of alternative techniques like water irrigation and CO2 insufflation.
Main Results:
- Unsedated colonoscopy is routinely performed in specific regions.
- Cultural factors significantly impact sedation preferences.
- Techniques such as warm water irrigation and CO2 insufflation enhance quality and tolerance.
Conclusions:
- Colonoscopy can be performed effectively without sedation.
- Alternative insufflation methods improve patient experience.
- Cultural context is crucial in determining colonoscopy sedation protocols.
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