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Updated: May 22, 2026

3D Cine Magnetic Resonance Imaging of Respiratory Motion in Mechanically Ventilated Mice and Rats
Published on: September 19, 2025
Prospective respiratory motion correction for coronary MR angiography using a 2D image navigator
Markus Henningsson1, Jouke Smink, Reza Razavi
1Division of Imaging Sciences and Biomedical Engineering, King's College London, London, United Kingdom. markus.henningsson@kcl.ac.uk
A novel 2D navigator (2Dnav) improves respiratory motion correction in coronary magnetic resonance angiography, outperforming traditional 1D navigators (1Dnav) without gating for better image quality.
Area of Science:
- Cardiovascular Imaging
- Medical Physics
- Biomedical Engineering
Background:
- Respiratory motion significantly degrades coronary magnetic resonance angiography (CMRA) image quality.
- Current motion correction relies on 1D navigators (1Dnav) with limitations in accurately capturing complex respiratory motion.
Purpose of the Study:
- To introduce and evaluate a novel 2D navigator (2Dnav) for prospective respiratory motion correction in CMRA.
- To compare the performance of 2Dnav against conventional 1Dnav in reducing respiratory motion artifacts.
Main Methods:
- Comparison of 1Dnav and 2Dnav in 2D real-time imaging experiments with healthy subjects and a moving phantom.
- Acquisition of high-resolution 3D CM angiograms using both 1Dnav and 2Dnav correction.
- Assessment of objective and subjective image quality, including residual motion and visual scores.
Main Results:
- 1Dnav and 2Dnav demonstrated comparable performance with a 10 mm gating window.
- Without respiratory gating, 2Dnav achieved image quality similar to 1Dnav with 10 mm gating.
- 1Dnav without gating resulted in lower visual scores for all coronary arteries compared to 10 mm gating.
Conclusions:
- The proposed 2Dnav offers improved prospective respiratory motion correction for CMRA, particularly beneficial in scenarios without strict gating.
- 2Dnav enhances image quality in CMRA by effectively correcting translational motion in multiple directions.
- This novel approach holds potential for improving diagnostic accuracy in CMRA by reducing motion-related artifacts.
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