Microarrays and cancer diagnosis

Cancer can be considered a "developmental disorder" because it involves a disruption in the normal development of cells, in terms of both differentiation and proliferation (Dean M,1998). Cancer cells generally contain the full complement of biomolecules that are necessary for survival, proliferation, differentiation, cell death, and expression of cell type-specific function. Human Cancer diagnosis and classification by Microarray analysis has yet to be widely accepted despite the exponential increase in microarray studies reported in the literatures. Additionally, recent microarrays were inspired by the nucleotide-based technology, which have created to better define the molecular basis of malignancy which have shown that microarray have clinical utility in cancer diagnosis, risk stratification, and patient management.