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Reporter Genes

Reporter Genes

Reporter genes are a type of protein-coding gene that are often tagged to a gene of interest. Once inside a target cell, reporter genes usually produce visually identifiable characteristics like fluorescence and luminescence when expressed along with the gene of interest. Thus, reporter genes “report” the presence or absence of genes of interest in an organism, determine the gene expression pattern, or track the physical location of a DNA segment or protein in the cell.
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A gene is a stretch of DNA that serves as the blueprint for functional RNAs and proteins. Since DNA is comprised of nucleotides and proteins are comprised of amino acids, a mediator is required to convert the information encoded in DNA into proteins. This mediator is the messenger RNA (mRNA). mRNA copies the blueprint from DNA by a process called transcription. In eukaryotes, transcription occurs in the nucleus by complementary base-pairing with the DNA template. The mRNA is then processed and...

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Gene expression is the process in which DNA directs the synthesis of functional products, that is, proteins. Cells can regulate gene expression at various stages. It allows organisms to generate different cell types and enables cells to adapt to internal and external factors.
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Related Experiment Video

Updated: May 21, 2026

Determining Genetic Expression Profiles in C. elegans Using Microarray and Real-time PCR

Determining Genetic Expression Profiles in C. elegans Using Microarray and Real-time PCR

Published on: July 30, 2011

An gene expression pattern.

Manjul Tiwari¹

¹Department of Oral Pathology and Microbiology, School of Dental Sciences, Sharda University, Greater Noida, Uttar Pradesh, India.

Journal of Natural Science, Biology, and Medicine

|June 13, 2012

Summary

DNA microarray technology offers powerful tools for molecular biologists. Custom-made DNA microarrays are now accessible for academic labs, aiding future scientific discoveries.

Area of Science:

Molecular Biology
Genomics
Biotechnology

Background:

DNA microarray technology is a significant advancement in molecular biology.
Availability of annotated genomic sequences and high-precision robotics facilitates microarray manufacturing.

Purpose of the Study:

To highlight the accessibility and production of DNA microarrays for academic research.
To emphasize the importance of tailored microarrays for scientific inquiry.

Main Methods:

Leveraging high-precision robotics for manufacturing.
Utilizing annotated DNA sequences from various genomes.
Requires careful management of biological and physical resources.

Main Results:

Keywords:

DNA Library gene microarray microarray robotic printer

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Last Updated: May 21, 2026

Determining Genetic Expression Profiles in C. elegans Using Microarray and Real-time PCR

Determining Genetic Expression Profiles in C. elegans Using Microarray and Real-time PCR

Published on: July 30, 2011

An Allele-specific Gene Expression Assay to Test the Functional Basis of Genetic Associations

An Allele-specific Gene Expression Assay to Test the Functional Basis of Genetic Associations

Published on: November 3, 2010

Single-cell Gene Expression Profiling Using FACS and qPCR with Internal Standards

Single-cell Gene Expression Profiling Using FACS and qPCR with Internal Standards

Published on: February 25, 2017

Microarray production is now feasible for average academic laboratories.

The process, while labor-intensive, yields custom-tailored microarrays.

Conclusions:

DNA microarrays are an essential tool for modern molecular biology research.
Accessible production empowers researchers to address complex scientific questions.