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Updated: May 22, 2026

Antigenic Liposomes for Generation of Disease-specific Antibodies
Published on: October 25, 2018
Muscle-specific kinase-antibody-positive myasthenia gravis after autologous bone marrow transplantation
Kavita Mohindra Grover1, Naganand Sripathi, Stanton Bernard Elias
1Department of Neurology, Henry Ford Hospital, Detroit, MI, USA. kgrover1@hfhs.org
Abstract:
A 44-year-old man presented with oculobulbar weakness approximately 5 years after autologous bone marrow transplantation (BMT). His workup led to the diagnosis of muscle-specific kinase-antibody-related myasthenia gravis (MG). There has been only one case report of muscle-specific kinase-antibody-positive MG after BMT, which was allogeneic. We report the first case of autologous BMT-associated MG with muscle-specific kinase antibody. The pathogenic mechanisms of immune dysregulation leading to MG after BMT are discussed.
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