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Related Concept Videos

Development of Blood Vessels01:07

Development of Blood Vessels

The development of the vascular system in a fetus is a complex and intricate process that begins as early as 15 to 16 days post-conception. This process starts outside the embryo, specifically in the mesoderm of the yolk sac, chorion, and connecting stalk. Approximately two days later, the formation of blood vessels occurs within the embryo itself.
The initial formation of this system is facilitated by the small amount of yolk present in the ovum and yolk sac. Blood vessels originate from...
Esophageal Varices-I: Introduction01:24

Esophageal Varices-I: Introduction

Esophageal varices are dilated, tortuous veins which are found mainly in the submucosa of the lower esophagus but which may also appear higher up or extend into the stomach. They develop due to increased pressure in the portal venous system, often as a result of liver cirrhosis. This condition scars and damages the liver, impeding normal blood flow through the portal vein. To compensate, blood seeks alternative pathways, forming fragile new vessels (varices) in the esophagus and stomach. These...
Hemorrhagic Stroke ll: Pathophysiology01:29

Hemorrhagic Stroke ll: Pathophysiology

A hemorrhagic stroke develops when a cerebral blood vessel ruptures, allowing blood to escape into the surrounding brain tissue, as in intracerebral hemorrhage (ICH), or into the subarachnoid space, as in subarachnoid hemorrhage (SAH). Because the skull is a rigid compartment, the sudden presence of extravascular blood rapidly increases intracranial pressure and compresses adjacent neural structures, leading to immediate tissue injury and impaired cerebral perfusion.Mass Effect and Primary...
Regulation of Angiogenesis and Blood Supply01:24

Regulation of Angiogenesis and Blood Supply

Rapidly dividing tumors, embryos, and wounded tissues require more oxygen than usual, lowering the oxygen concentration in the blood. At low oxygen or hypoxic conditions, an oxygen-sensitive transcription factor called the hypoxia-inducible factor 1 or HIF1 is activated. HIF1 is a dimeric protein of alpha (ɑ) and beta (β) subunits.  Under optimal oxygen conditions, HIF1β is present in the nucleus while HIF1ɑ remains in the cytosol. HIF1ɑ is hydroxylated by prolyl hydroxylase and factor...
Hemorrhagic Stroke l: Introduction01:17

Hemorrhagic Stroke l: Introduction

A hemorrhagic stroke is an acute neurological event that occurs when a weakened cerebral blood vessel ruptures, allowing blood to accumulate within or around the brain. The sudden release of blood forms a focal hematoma that increases intracranial pressure, displaces neural tissue, and can obstruct cerebrospinal fluid pathways. These effects may be compounded by intraventricular extension of the hemorrhage, cerebral edema, or compression of adjacent structures, all of which contribute to...
Mechanism of Angiogenesis01:10

Mechanism of Angiogenesis

Blood vessel formation starts early during embryonic development, around day 7. In the extraembryonic yolk sac, mesodermal precursor cells called hemangioblast proliferate and differentiate into angioblast. Angioblasts express vascular endothelial growth factor receptor 2 or VEGFR2, which binds VEGF-A, a proangiogenic factor, guiding blood vessel formation. VEGF signaling promotes angioblasts to form a blood island in the developing embryo. Angioblasts further differentiate, giving rise to...

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Related Experiment Video

Updated: May 22, 2026

Laparoscopic Anatomical Right Hemihepatectomy via the In Situ Anterior Approach
05:30

Laparoscopic Anatomical Right Hemihepatectomy via the In Situ Anterior Approach

Published on: August 8, 2025

Uterine hemangioma: a rare pathologic entity.

Wan-Yi Chou1, Hui-Wen Chang

  • 1Department of Pathology, China Medical University Hospital, 2 Yuh-Der Road, Taichung City, Taiwan. d15334@mail.cmuh.org.tw

Archives of Pathology & Laboratory Medicine
|May 1, 2012
PubMed
Summary
This summary is machine-generated.

Uterine hemangioma, a rare benign tumor, often presents with heavy menstrual bleeding. Accurate diagnosis is crucial to avoid overtreatment in women of reproductive age, with hysterectomy offering an excellent prognosis.

Related Experiment Videos

Last Updated: May 22, 2026

Laparoscopic Anatomical Right Hemihepatectomy via the In Situ Anterior Approach
05:30

Laparoscopic Anatomical Right Hemihepatectomy via the In Situ Anterior Approach

Published on: August 8, 2025

Area of Science:

  • Gynecology
  • Pathology
  • Oncology

Background:

  • Uterine hemangioma is a rare benign tumor.
  • It typically presents with menorrhagia or pregnancy complications.
  • Fewer than 50 cases are reported in current literature.

Purpose of the Study:

  • To report on the incidence and diagnosis of uterine hemangioma.
  • To highlight the diagnostic challenges and differential diagnoses.
  • To emphasize the importance of accurate diagnosis for appropriate management.

Main Methods:

  • Retrospective review of 5 cases of uterine hemangioma identified from 3700 hysterectomies.
  • Analysis of preoperative diagnoses and diagnostic modalities.
  • Histologic examination as the definitive diagnostic tool.

Main Results:

  • Five cases of uterine hemangioma were identified between January 2006 and December 2010.
  • Adenomyosis was the most common preoperative diagnosis.
  • Preoperative diagnostic methods like ultrasound and hysterography were often uninformative.

Conclusions:

  • Accurate diagnosis of uterine hemangioma is essential to prevent overtreatment in reproductive-age women.
  • While treatment options are debated, hysterectomy provides an excellent prognosis.
  • Further research into congenital and acquired uterine hemangioma is warranted.