Quality of 4-hourly ejaculates--levels of calcium and magnesium
J Valsa1, K P Skandhan, P H Gusani
1Department of Physiology, Government Medical College, Surat, India.
Insights
Frequent ejaculation over 16 hours decreased semen volume and sperm count but improved sperm motility. Increased seminal calcium and magnesium may help clear motility inhibitors.
Area of Science:
- Reproductive biology
- Human physiology
- Andrology
Background:
- Understanding the physiological effects of frequent ejaculation on semen quality is crucial for reproductive health.
- Previous research has explored ejaculation frequency, but the impact of sustained, frequent ejaculation over extended periods requires further investigation.
Purpose of the Study:
- To investigate the changes in semen parameters, including volume, sperm count, and motility, during a four-hourly ejaculation regimen.
- To analyze the levels of seminal plasma and intracellular calcium and magnesium in relation to ejaculation frequency.
- To explore the potential role of these minerals in modulating sperm motility.
Main Methods:
- A four-hourly ejaculation study involving eleven healthy male subjects.
- Semen samples were collected over a period of up to 16 hours.
- Analysis included semen volume, sperm count, sperm motility (total, active, sluggish), and seminal plasma and intracellular calcium and magnesium concentrations.
Main Results:
- A decrease in semen volume and sperm count was observed from the first to the last ejaculate.
- Sperm motility, particularly actively motile spermatozoa, progressively increased, while sluggish spermatozoa decreased.
- Significant increases in seminal plasma calcium and magnesium, as well as intracellular magnesium, were noted from the first to the fourth ejaculate.
Conclusions:
- Frequent ejaculation over 16 hours leads to reduced semen volume and sperm count but enhanced sperm motility.
- Elevated calcium and magnesium levels may play a role in improving sperm motility by mitigating inhibitory factors.
- These findings suggest a potential benefit of calcium and magnesium in maintaining sperm motility under conditions of frequent ejaculation.
Abstract:
A four-hourly ejaculation study was conducted in which eleven normal healthy subjects participated. Five of them discontinued after submitting three samples. One alone was present for submission at the end of 16 h (fifth ejaculate), which was his last submission. Physical exhaustion was the sole reason for all participants for their discontinuation from the study. The result showed a decrease in semen volume and sperm count from first to last ejaculate. The increase in motility was probably due to reduction in exposure time to sperm motility inhibitory factors. In general, total motile spermatozoa as well as actively motile spermatozoa progressively increased from first to last ejaculate at the cost of sluggish spermatozoa. A significant increase in seminal plasma calcium and magnesium was seen as well as a significant increase in magnesium inside the cell from the first to the fourth ejaculate. Considering the quality of semen, which was good in sperm count and excellent in motility, calcium and magnesium may be helpful in cleaning motility inhibitory factors of spermatozoa.
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