Related Experiment Videos
Antiurolithiatic activity of coleus Aromaticus Benth. In Rats
R B Ghosh1, T K Sur, L N Maity
1Department of Kayachikitsa, Institute of PG Ayurvedic Education & Research, Calcutta-9, India.
Ancient Science of Life
|May 5, 2012
Summary
The water extract of Coleus aromaticus leaves shows promise in preventing kidney stones. Studies indicate it effectively reduces calcium oxalate deposition in rats, suggesting therapeutic potential for urinary tract stone formation.
Area of Science:
- Pharmacology
- Nephrology
- Ethnobotany
Background:
- Kidney stones, particularly calcium oxalate stones, are a common ailment.
- Traditional medicine often utilizes plant-based remedies for various health conditions.
Purpose of the Study:
- To investigate the antiurolithiatic activity of Coleus aromaticus leaf extract.
- To evaluate the efficacy of Coleus aromaticus in preventing calcium oxalate deposition.
Main Methods:
- Induction of calcium oxalate stones in male albino rats using sodium oxalate.
- Administration of Coleus aromaticus water extract (0.5 g/kg and 1.0 g/kg) orally for 30 days.
- Assessment of calcium oxalate deposition in the kidneys.
Main Results:
- The water extract of Coleus aromaticus significantly reduced calcium oxalate deposition.
- Both tested dosages (0.5 g/kg and 1.0 g/kg) demonstrated effectiveness.
Conclusions:
- Coleus aromaticus leaves possess antiurolithiatic properties.
- The extract may be beneficial in managing calcium oxalate urolithiasis.
- Further research into Coleus aromaticus for kidney stone therapy is warranted.
Related Concept Videos
01:26Urinary Tract Calculi II: Pathophysiology and Clinical Manifestations
Renal calculi, commonly termed kidney stones, are crystalline solid masses that form in the kidneys but can occur at any point within the urinary system, encompassing the kidneys, ureters, bladder, and urethra.The pathophysiology of renal stones involves several key factors: supersaturation of the urine with stone-forming constituents, changes in urine pH, a decrease in urine volume, and the presence of substances that promote or inhibit stone formation.Supersaturation of Urine: This is the...
01:30Urinary Tract Calculi III: Medical Management
The diagnosis of renal calculi involves several imaging techniques, including non-contrast CT scans and ultrasound. These methods help visualize kidney stones, assess their size and location, and detect possible obstructions. Additionally, Measuring urine pH is useful for diagnosing specific stone types, such as struvite (alkaline pH) and uric acid stones (acidic pH). Cystine stones are primarily linked to cystinuria, a genetic condition. A urinalysis helps detect blood in the urine (hematuria)...