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Cross-phase modulation spectral shifting: nonlinear phase contrast in a pump-probe microscope
Biomedical Optics Express
|May 9, 2012
Abstract:
Microscopy with nonlinear phase contrast is achieved by a simple modification to a nonlinear pump-probe microscope. The technique measures cross-phase modulation by detecting a pump-induced spectral shift in the probe pulse. Images with nonlinear phase contrast are acquired both in transparent and absorptive media. In paraffin-embedded biopsy sections, cross-phase modulation complements the chemically-specific pump-probe images with structural context.

