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Updated: May 22, 2026

DNAzyme 10-23 - Based Nanomachines for Nucleic Acid Recognition
Published on: February 9, 2024
Reusable molecular sensor based on photonic activation control of DNA probes
Takahiro Nishimura1, Yusuke Ogura, Jun Tanida
1Graduate School of Information Science and Technology, Osaka University, 1-5 Yamadaoka, Suita, Osaka, 5650871, Japan.
Abstract:
We propose a photoactivatable and resettable molecular sensor using DNA probes. The functionality is achieved by reversible change of DNA structure induced via photonic signals. Based on the mechanism, the sensor can detect target molecules at a desired instant and can be returned to its initial state after detection. The experimental results demonstrate that the concentrations of the target molecules are detected correctly and repeatedly according to the light signal.
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