Related Experiment Video
Updated: May 22, 2026

Improved Home Blood Pressure Control by CT-guided Ozone-mediated Renal Denervation for Patients with Resistant Hypertension
Published on: June 6, 2025
New proofs concerning benefits from time-scheduled BP-lowering therapy
1Medical Clinic, Clinical Emergency Hospital Ilfov County, Carol Davila University of Medicine and Pharmacy, Bucharest, Romania. drhoriabalan@yahoo.com
Insights
High blood pressure (HBP) is a major health issue. Ambulatory blood pressure monitoring (ABPM) and chronotherapy are crucial for managing HBP and preventing cardiovascular disease, especially in women.
Area of Science:
- Cardiology
- Hypertension Research
- Preventive Medicine
Background:
- High blood pressure (HBP) is a significant global health concern, often termed the "silent killer."
- HBP is a primary reversible risk factor for cardiovascular diseases (CVD).
- Nocturnal blood pressure is a critical predictor of cardiovascular prognosis, particularly in women.
Purpose of the Study:
- To review recent evidence supporting Ambulatory Blood Pressure Monitoring (ABPM).
- To highlight the importance of ABPM in assessing nocturnal blood pressure.
- To summarize findings favoring chronotherapy as the gold standard for HBP management.
Main Methods:
- Systematic review of recently published studies on ABPM and HBP chronotherapy.
- Analysis of data focusing on the prognostic value of nocturnal blood pressure.
- Evaluation of evidence for chronotherapy in HBP management.
Main Results:
- ABPM is essential for evaluating nocturnal blood pressure, a key prognostic indicator.
- Nocturnal blood pressure values are highly predictive of cardiovascular outcomes, with greater significance in women.
- Recent studies provide strong evidence supporting chronotherapy for effective HBP management.
Conclusions:
- ABPM is a vital tool for assessing cardiovascular risk associated with HBP.
- Chronotherapy represents the gold standard in the clinical management of hypertension.
- Understanding and managing nocturnal blood pressure is critical for improving cardiovascular health outcomes.
Abstract:
High blood pressure (HBP) is one of the most important medical and social problems of the present era; she is considered not only the "silent killer' but also the most important reversible risk factor for cardio-vascular diseases (CVD). In the past two years important proofs have been published in favor of ABPM, a mandatory tool for the assessment of the nocturnal body pressure values, the most important predictor for the cardio-vascular prognosis, even more important in women than in men. The present paper is summarizing the data from the last published studies, concerning very significant and reliable proofs, in favor of the chronotherapy of HBP, the gold standard for good practice in the management of this disease.
Related Concept Videos
Chronopharmacokinetics: Circadian Rhythms and Influence on Drug Response
The time of drug administration is an important factor to consider, as it can influence the toxic dose of a drug. For example, a study conducted by Prins et al. in 1997 examined the effects of the timing of...
Atherosclerosis III: Management
Adrenergic Antagonists: Pharmacological Actions of β-Receptor Blockers
Adrenergic Antagonists: ɑ and β-Receptor Blockers
Pre-Procedural Guidelines for Assessing Blood Pressure