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Cellulose and Pectic Polysaccharides01:15

Cellulose and Pectic Polysaccharides

Every plant cell has a cell wall that protects the cell, provides structural support, and gives the cell shape. Cellulose, the main structural component of the plant cell wall, makes up over 30% of plant matter. It is the most abundant organic compound on earth.  Cellulose is an unbranched polysaccharide composed of linear chains of glucose molecules linked by β (1→4) glycosidic bonds.
As a cell matures, its cell wall specializes according to its type. For example, the parenchyma cells of...

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Published on: February 26, 2021

Ethylcellulose microparticles: a review.

Ghulam Murtaza1

  • 1Department of Pharmaceutics, COMSATS Institute of Information Technology, Abbottabad, Pakistan. gmdogar356@gmail.com

Acta Poloniae Pharmaceutica
|May 12, 2012
PubMed
Summary
This summary is machine-generated.

Ethylcellulose (EC) microcapsules offer controlled drug release and protect core substances. Their particle characteristics and formulation parameters allow fine-tuning of drug release kinetics for effective drug delivery.

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Area of Science:

  • Pharmaceutical Sciences
  • Materials Science

Background:

  • Ethylcellulose (EC) microencapsulation is widely researched for extended drug release and substance protection.
  • EC microcapsules exhibit particle characteristics crucial for regulating drug release rates based on drug-EC interactions.

Purpose of the Study:

  • To review microencapsulation techniques, core substances, and preparation/characterization fundamentals of EC microcapsules.
  • To highlight EC microcapsules as mini-osmotic pumps with tunable release kinetics.

Main Methods:

  • Review of literature on EC microencapsulation techniques.
  • Analysis of in vitro evaluation data for EC microcapsules' particle characteristics.
  • Discussion of factors influencing drug release kinetics.

Main Results:

  • EC microcapsule particle characteristics effectively control drug release rates.
  • Release kinetics can be precisely adjusted by modifying formulation parameters and EC properties.
  • EC microcapsules function as mini-osmotic pumps.

Conclusions:

  • EC microcapsules are versatile systems for controlled drug delivery.
  • Fine-tuning of release profiles is achievable through formulation optimization and selection of EC grades.
  • Further research into EC microencapsulation holds promise for advanced drug delivery systems.