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Updated: May 22, 2026

Occlusion of the Great and Small Saphenous Vein Using Copolymeric Glue Based on N-Butyl Cyanoacrylate and Methacryloxy Sulfolane
Published on: December 9, 2022
[Leiomyosarcoma of the great saphenous vein]
Diana Mathilde Røpcke1, Jakob Ahrndt Lorenzen, Peter Holmberg Jørgensen
1Plastikkirurgisk Afdeling Z, Aarhus Universitetshospital, Aalborg Sygehus, Sdr. Skovvej 3B, 9000 Aalborg, Denmark. dmr@dadlnet.dk
Abstract:
A 63 year-old woman presented with a painful subcutaneous tumour on her right thigh. After ultrasound, suspicion of metastasis from malignant melanoma was raised. The tumour was subsequently excised. Histology proved the tumour to be a leiomyosarcoma (LMS) of the great saphenous vein. The patient was referred to a sarcoma center for further treatment. LMS of the great saphenous vein is a very rare tumour. From 1919 to 2004, 25 cases are reported in the literature. Diagnosis is aided by magnetic resonance imaging and Doppler ultrasound. Treatment is wide excision and sometimes radiotherapy. This kind of tumour can metastazise to the lungs. The survival prognosis is poor.
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