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Updated: May 22, 2026

Amide Coupling Reaction for the Synthesis of Bispyridine-based Ligands and Their Complexation to Platinum as Dinuclear Anticancer Agents
Published on: May 28, 2014
(Di-2-pyridyl-amine-κ(2)N(2),N(2'))diiodidoplatinum(II)
1School of Applied Chemical Engineering, The Research Institute of Catalysis, Chonnam National University, Gwangju 500-757, Republic of Korea.
Abstract:
The Pt(II) ion in the title complex, [PtI(2)(C(10)H(9)N(3))], is four-coordinated in a distorted square-planar environment defined by the two pyridine N atoms of the chelating di-2-pyridyl-amine (dpa) ligand and by two I(-) anions. The dpa ligand is not planar, the dihedral angle between the pyridine rings being 52.8 (3)°. Pairs of complex mol-ecules are assembled through inter-molecular N-H⋯I hydrogen bonds, forming a dimer-type species. The complexes are stacked in columns along the b axis and display several inter-molecular π-π inter-actions between the pyridine rings, with a shortest ring centroid-centroid distance of 3.997 (5) Å.
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