Related Experiment Video
Updated: May 22, 2026

04:09
Minimal Invasive Resection of Large Retrosternal Thyroid Goiter
Published on: September 20, 2024
Severe group a streptococcus surgical site infection after thyroid lobectomy
Joelle B Karlik1, Vincent Duron, Leonard A Mermel
1Alpert Medical School of Brown University, Providence, Rhode Island 10014, USA. Joelle.Karlik@brown.edu
Surgical Infections
|May 23, 2012
Summary
Surgical site infections after thyroidectomy are rare but dangerous. This case highlights a severe Group A Streptococcus (GAS) infection requiring emergent surgery and antibiotics, emphasizing the need for high clinical suspicion.
Area of Science:
- Surgical Oncology
- Infectious Diseases
- Head and Neck Surgery
Background:
- Thyroidectomy rarely results in surgical site infection (SSI), but complications can be life-threatening due to proximity to vital structures.
- Severe SSIs, particularly necrotizing fasciitis, are often caused by Group A Streptococcus (GAS).
- Limited literature exists on managing necrotizing soft-tissue infections post-thyroid resection.
Observation:
- A patient developed severe soft tissue infection with airway compromise two days after thyroidectomy.
- Computed tomography revealed swelling, and emergency incision and drainage were performed.
- The patient required re-exploration due to worsening erythema and swelling.
Findings:
- The infection was identified as Group A Streptococcus (GAS), potentially acquired from a family member with pharyngitis.
- This represents the first reported case of GAS infection post-thyroidectomy linked to family exposure.
- Successful treatment involved emergent operative debridement and systemic antibiotics.
Implications:
- Highlights the importance of considering GAS in severe post-thyroidectomy infections.
- Emphasizes the need for prompt surgical intervention and antibiotic therapy.
- Suggests potential for community-acquired infections to complicate surgical outcomes.
Related Concept Videos
Tonsillitis I: Introduction
Tonsillitis is inflammation of the tonsils, which are two lymphoid tissue masses at the back of the throat. This condition can cause discomfort and irritation in the throat.
Etiology
Three primary contributing factors have been identified.
Etiology
Three primary contributing factors have been identified.
Graves' Disease I: Introduction
Graves' disease is an autoimmune disorder that causes hyperthyroidism, or overactivity of the thyroid gland. It results from autoantibodies called thyroid-stimulating immunoglobulins (TSIs), which bind to thyroid-stimulating hormone (TSH) receptors, leading to overstimulation of hormone production and a hypermetabolic state.EtiologyAlthough considered idiopathic, Graves’ disease has well-established contributing factors. There is a strong genetic component, with increased prevalence in...
Staphylococcal Skin Infections
Staphylococcus aureus is a Gram-positive coccus that resides harmlessly on the skin and mucous membranes of healthy individuals. When the skin barrier is breached, it can shift from a commensal to an opportunistic pathogen. This transition is facilitated by surface adhesins, such as clumping factor B and S. aureus surface protein G (SasG), which bind to structural proteins, including loricrin and cytokeratin, in the damaged epidermis. Protein A, another key factor, binds the Fc region of...
Tonsillitis II: Management
This lesson will focus on the different treatment options for managing tonsillitis, which typically depend on the cause and severity.
The Thyroid Gland
The thyroid gland is a small, butterfly-shaped gland located in the neck and covers the anterior surface of the trachea. The gland has two lateral lobes connected by a thin tissue mass called the isthmus. Internally, each lobe comprises many small spherical structures known as thyroid follicles, surrounded by a network of blood vessels.
The follicles have a central cavity lined by simple cuboidal to squamous epithelial cells called follicular cells. These cells produce the glycoprotein...
The follicles have a central cavity lined by simple cuboidal to squamous epithelial cells called follicular cells. These cells produce the glycoprotein...

