Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Atherosclerosis III: Management01:26

Atherosclerosis III: Management

Management of atherosclerosis involves an integrated strategy encompassing pharmacological treatment, surgical interventions, lifestyle changes, and nutrition therapy to address the multifactorial nature of the disease.Pharmacological TherapyA cornerstone of atherosclerosis management is the use of pharmacological agents. Statins, such as atorvastatin, are pivotal in inhibiting HMG-CoA reductase, an enzyme that catalyzes an initial step in cholesterol synthesis in the liver. This reduction in...
Cardiomyopathy V: Interprofessional Care01:29

Cardiomyopathy V: Interprofessional Care

Managing cardiomyopathy involves addressing underlying or precipitating causes, treating heart failure with medications, and implementing dietary changes and a balanced exercise and rest regimen.Lifestyle ModificationsCardiomyopathy patients should adopt a low-sodium diet to reduce fluid retention and manage heart failure. A personalized exercise and rest plan helps maintain physical fitness without overstraining the heart. Avoiding alcohol and tobacco is essential to prevent further damage to...
Hypertension IV: Drug Therapy and Lifestyle Modifications01:28

Hypertension IV: Drug Therapy and Lifestyle Modifications

Multiple classes of antihypertensive medications are employed in treating hypertension. The most commonly recommended first-line treatments include:Thiazide Diuretics, such as chlorthalidone, increase sodium and water excretion from the body, reducing blood volume and blood pressure.Angiotensin-converting enzyme inhibitors, like lisinopril, block the conversion of angiotensin I to II, a potent vasoconstrictor lowering blood pressure.Angiotensin II Receptor Blockers (ARBs) prevent angiotensin II...
Coronary Artery Disease IV: Preventive Measures01:26

Coronary Artery Disease IV: Preventive Measures

Effective preventive measures for coronary artery disease (CAD) focus on controlling modifiable risk factors, including cholesterol abnormalities and lifestyle changes.Cholesterol ManagementFirst, the Mediterranean diet and the American Heart Association advocate for maintaining low-density lipoprotein (LDL) cholesterol levels below 100 mg/dL, with a more stringent recommendation of below 70 mg/dL for individuals at high risk. LDL cholesterol, often termed "bad cholesterol," can lead to the...
Peripheral Artery Disease III: Interprofessional Care01:27

Peripheral Artery Disease III: Interprofessional Care

Peripheral Artery Disease (PAD) is characterized by narrowed arteries that diminish blood flow to the extremities. Effective management of PAD requires an interprofessional approach involving various healthcare professionals. The critical aspects of interprofessional care for PAD patients focus on risk factor modification, drug therapy, exercise therapy, nutrition therapy, critical limb ischemia care, and interventional radiology and surgical procedures.The primary treatment goal for PAD...
Drug Therapy01:28

Drug Therapy

The advent of drug therapy has profoundly shaped modern mental health care, providing targeted treatments for a range of psychological disorders. Psychotherapeutic drugs, classified into antianxiety, antidepressant, and antipsychotic medications, address symptoms across anxiety disorders, mood disorders, and schizophrenia. While these medications have transformed patient outcomes, they require careful management due to their potential side effects and limitations.
Antianxiety Medications

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Social Medicine Approaches to Community-Integrated Diabetes Care: A Narrative Review of Clinic-Based Triaging and Closed-Loop Referral Interventions.

Journal of general internal medicine·2026
Same author

Health Care Utilization and Cancer Screening Among Patients with Neurodivergence in a Safety-Net Adult Primary Care Clinic.

Journal of general internal medicine·2026
Same author

Trends in End-Stage Kidney Disease Due to Reflux Nephropathy in Children and Young Adults.

Pediatrics·2026
Same author

Liver Fat and Iron Quantification With Spectral Localizer Radiographs From Photon-counting Detector CT.

Investigative radiology·2025
Same author

The Impact of Parkinson's Disease Psychosis on Caregiver Burden: A Systematic Literature Review.

Neuroepidemiology·2025
Same author

A Dangerous Retreat: Defunding AHRQ and the Threat to Diagnostic Safety.

Journal of general internal medicine·2025
Same journal

Assessment of comprehensive medication management incorporating a patient-completed medical and medication history form in community practice.

Journal of the American Pharmacists Association : JAPhA·2026
Same journal

Characterizing how community pharmacy teams engage with social drivers of health (SDOH) during routine workflow: A report from the medication safety research network of Indiana (Rx-SafeNet).

Journal of the American Pharmacists Association : JAPhA·2026
Same journal

Geographic disparities in board-certified ambulatory care pharmacists in Appalachia.

Journal of the American Pharmacists Association : JAPhA·2026
Same journal

Development of consensus criteria for problematic medications in active duty service members.

Journal of the American Pharmacists Association : JAPhA·2026
Same journal

Barriers and facilitators to pharmacy-based methadone dosing and dispensing: Semi-structured interviews with pharmacists.

Journal of the American Pharmacists Association : JAPhA·2026
Same journal

A bibliometric analysis describing the global scope of pharmacist roles (2000-2024).

Journal of the American Pharmacists Association : JAPhA·2026
See all related articles

Related Experiment Video

Updated: May 22, 2026

Digital Home-Monitoring of Patients after Kidney Transplantation: The MACCS Platform
07:13

Digital Home-Monitoring of Patients after Kidney Transplantation: The MACCS Platform

Published on: April 12, 2021

Targeting cardiovascular medication adherence interventions.

Sarah L Cutrona1, Niteesh K Choudhry, Michael A Fischer

  • 1Division of Pharmacoepidemiology and Pharmacoeconomics, Brigham and Women's Hospital, Harvard Medical School, Boston, USA. sarah.cutrona@umassmemorial.org

Journal of the American Pharmacists Association : Japha
|May 24, 2012
PubMed
Summary
This summary is machine-generated.

Targeting medication nonadherers with focused or dynamic interventions may improve effectiveness compared to broad approaches for all patients. Dynamic interventions show promise for better medication adherence outcomes.

Related Experiment Videos

Last Updated: May 22, 2026

Digital Home-Monitoring of Patients after Kidney Transplantation: The MACCS Platform
07:13

Digital Home-Monitoring of Patients after Kidney Transplantation: The MACCS Platform

Published on: April 12, 2021

Area of Science:

  • Pharmacology
  • Clinical Trials
  • Health Services Research

Background:

  • Medication adherence is crucial for managing chronic conditions like cardiovascular disease and diabetes.
  • Interventions to improve adherence vary in their targeting strategies, with implications for effectiveness.

Purpose of the Study:

  • To compare the effectiveness of broad, focused, and dynamic adherence interventions.
  • To determine optimal strategies for administering adherence interventions in clinical practice.

Main Methods:

  • Systematic literature search of randomized controlled trials (RCTs) from 1966-2009 in Medline and Embase.
  • Classified interventions as broad (all takers), focused (nonadherers), or dynamic (real-time targeting).
  • Calculated Cohen's d effect sizes to quantify intervention impact.

Main Results:

  • 59 RCTs met inclusion criteria out of 7,190 identified articles.
  • Broad interventions were less effective (18%) than focused (25%) or dynamic (32%) interventions.
  • Dynamic interventions using self-generated adherence data showed higher effectiveness (34.8%) than those using external data (20%).

Conclusions:

  • Adherence interventions targeting nonadherers demonstrate potential advantages over broad strategies.
  • Dynamic interventions, particularly those leveraging real-time adherence data, represent a promising area for future research and application.