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Long-term experience of patch graft failure after Ahmed Glaucoma Valve® surgery using donor dura and sclera
1Department of Ophthalmology, University of Cincinnati College of Medicine and Cincinnati Eye Institute, Cincinnati, Ohio, USA. zaltaah@uc.edu
Background And Objective:
To report the long-term incidence, timing, and experience of patch graft failure (PGF) after Ahmed Glaucoma Valve (AGV) (New World Medical, Inc., Rancho Cucamonga, CA) surgery in a large consecutive case series using donor dura mater and sclera sequentially as the allograft materials.
Patients And Methods:
The medical records of all AGV surgeries performed from June 1994 through December 2010 were retrospectively reviewed for cases of PGF.
Results:
Patch graft failure occurred in 44 (6.3%) of the initial 695 procedures using dura and in 65 (5.8%) of the subsequent 1,121 procedures using sclera (P = .64). The time interval after AGV surgery until the occurrence of PGF was significantly longer for dura (5.8 ± 3.8 years) than for sclera (2.7 ± 1.9 years) (P < .001).
Conclusion:
After an average of 4 years, PGF occurred in 109 (6%) of 1,816 consecutive AGV surgeries using donor dura and sclera allografts. PGF may be the most frequent long-term complication after AGV surgery.
