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Updated: May 22, 2026

Automated 3D Optical Coherence Tomography to Elucidate Biofilm Morphogenesis Over Large Spatial Scales
Published on: August 21, 2019
Ultrathin fiber probes with extended depth of focus for optical coherence tomography
Dirk Lorenser1, Xiaojie Yang, David D Sampson
1Optical+Biomedical Engineering Laboratory, School of Electrical, Electronic & Computer Engineering, The University of Western Australia, WA 6009, Australia. dirk.lorenser@uwa.edu.au
Abstract:
We report on a novel scheme for extending the depth of focus (DOF) of ultrathin (125 μm diameter) fiber probes for optical coherence tomography (OCT) using a simple phase mask consisting of graded-index (GRIN) fiber. The technique is compatible with existing all-in-fiber probe fabrication techniques, and our simulations show that it can provide a DOF gain of ~2 at a modest ~5 dB reduction of peak sensitivity. In a prototype device using commercially available GRIN fiber, a DOF gain of 1.55 is obtained, validated by beam profiling and OCT imaging.
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