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Intracoronary Acetylcholine Provocation Testing for Assessment of Coronary Vasomotor Disorders
Published on: August 18, 2016
Chest pain with ST-T changes on electrocardiogram and localized stenosis on coronary angiography could be a coronary
Bharat Jagiasi1, Prashant Nasa, Debabrata Dash
1Department of Critical Care Medicine, Fortis Raheja Hospital, Mumbai, India.
Insights
Coronary vasospasm, a cause of chest pain, can be diagnosed with provocative tests. This case highlights a transient stenosis in the left anterior descending artery, managed successfully with medication, avoiding invasive procedures.
Area of Science:
- Cardiology
- Vascular Medicine
Background:
- Coronary vasospasm is a condition causing chest pain at rest, often with ECG abnormalities and normal coronary angiograms.
- Provocative testing is typically required for definitive diagnosis but carries significant risks.
Observation:
- A patient presented with symptoms suggestive of coronary vasospasm.
- Coronary angiography revealed a localized, transient stenosis in the proximal left anterior descending artery.
Findings:
- The observed stenosis resolved spontaneously on subsequent angiographic views.
- The patient's condition improved with medical management alone, and coronary stenting was not required.
Implications:
- This case suggests that transient coronary artery stenosis can mimic or be associated with vasospasm.
- Non-invasive or less invasive diagnostic and management strategies may be considered in select cases.
- Careful interpretation of angiographic findings, especially dynamic changes, is crucial for appropriate patient management.
Abstract:
Coronary vasospasm is characterized by chest pain at rest with ST-T changes on electro cardiogram and coronary angiography showing virtually normal coronaries. The definitive diagnosis requires the stimulation of coronary vasospasm using provocative agents, which can be life threatening. We present a case where localized stenosis of proximal left anterior descending artery was observed on the coronary angiography, which disappeared on subsequent views, and hence, coronary stenting was deferred and patient responded well to medical management alone.
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