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Updated: May 22, 2026

Ultrasound-guided Botulinum Toxin-A Injections: A Method of Treating Sialorrhea
Published on: November 9, 2016
[Botulinum toxin in focal hyperhidrosis. An update].
1Klinik und Poliklinik für Dermatologie, Venerologie und Allergologie, Universitätsklinikum Würzburg, Josef-Schneider-Str. 2, 97080, Würzburg, Deutschland.
Botulinum toxin type A injections effectively treat primary axillary hyperhidrosis for about seven months, significantly improving quality of life. Its use in palmoplantar hyperhidrosis is limited due to pain and shorter duration.
Area of Science:
- Dermatology
- Neurology
Context:
- Intralesional injections of botulinum toxin type A are an established treatment for primary axillary hyperhidrosis.
- Axillary hyperhidrosis significantly impairs quality of life.
Purpose:
- To evaluate the efficacy and duration of botulinum toxin type A in treating primary axillary hyperhidrosis.
- To discuss the limitations of botulinum toxin in treating palmoplantar hyperhidrosis.
Summary:
- Botulinum toxin type A injections reduce sweat production by approximately one-sixth, with effects lasting an average of seven months.
- This treatment leads to significant restoration of quality of life in patients with primary axillary hyperhidrosis.
- Botulinum toxin type B shows comparable efficacy but with more systemic adverse events.
Impact:
- Botulinum toxin type A offers a highly effective, safe, and minimally invasive option for axillary hyperhidrosis.
- The findings support the continued use and exploration of botulinum toxin for various forms of hyperhidrosis.
- Understanding the limitations in palmoplantar hyperhidrosis guides future treatment strategies.
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