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Multicentric giant cell tumor in adolescents: three case reports
Sung-Taek Jung1, Hyeong-Won Park, Keun-Bae Lee
1Department of Orthopaedic Surgery, Chonnam National University Medical School and Hospital, Gwangju, Korea.
Journal of Pediatric Orthopedics. Part B
|May 31, 2012
Summary
Multicentric giant cell tumors are rare in adolescents with open physes. This study presents three cases and a literature review, highlighting this uncommon bone tumor presentation in young patients.
Area of Science:
- Orthopedic Oncology
- Pediatric Bone Tumors
Background:
- Giant cell tumor of bone (GCTB) is typically a benign but locally aggressive neoplasm.
- Multicentric presentation of GCTB is uncommon, especially in skeletally immature individuals.
Purpose of the Study:
- To describe the rare occurrence of multicentric giant cell tumor in adolescents with open physes.
- To review existing literature on similar cases to provide clinical context.
Main Methods:
- Case series reporting on three adolescent patients diagnosed with multicentric GCTB.
- Comprehensive literature search for previously reported cases of multicentric GCTB in adolescents.
Main Results:
- Three adolescent cases of multicentric GCTB with open physes are presented.
- Literature review identified limited comparable cases, underscoring the rarity.
Conclusions:
- Multicentric giant cell tumor, though rare, can occur in adolescents with open physes.
- Further research and case reporting are needed to understand the behavior and optimal management of this rare entity in pediatric populations.
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